【abstract】The Ministry of Education issued the Administrative Measures for the Filing of Mobile Internet Applications in Education and the Action Plan for the Special Governance of Mobile Internet Applications in Management Services Education in Colleges and Universities, deployed and launched the 2019 online learning space application popularization activities, the selection and recommendation of educational informatization teaching application community projects and the annual development survey of educational informatization, and completed the data submission to the national population basic information database. Liaoning, Yunnan, Ningxia and other places have launched activities to popularize the application of online learning space. Jilin, Heilongjiang, Hunan and other places organized special training on "National Education Informatization Management Information System".

　　★Central Network Information Important Work Deployment

　　Implementation of key tasks (omitted)

　　★Progress in key work of educational informatization

　　Education Mobile Internet Application Management The General Office of the Ministry of Education issued the Administrative Measures for the Filing of Education Mobile Internet Applications, which made specific arrangements for the filing work. The Network Information Office of the Ministry of Education issued the "Action Plan for Special Governance of Mobile Internet Applications in Management Services Education in Colleges and Universities" to address the problem of the proliferation of mobile Internet applications in management services education in colleges and universities due to formalism.

　　Co-construction and Sharing of Quality Education Resources The Ministry of Education publicized 10,007 ministerial-level "excellent courses" selected by the activity of "one teacher, one excellent course and one famous teacher". Organized 39 cross-regional teaching and research activities in Leibo, Sichuan and Zhouqu, Gansu. There are 111,000 new registered users and 301 new client users on the website Love Courses. The MOOC mobile terminal of China University has been downloaded and installed for 33.6 million times. The platform is teaching 15,000 courses, with 123,000 new materials and 5.953 million new registrations.

　　Online learning space is accessible to everyone. In Changchun, the 2019 online learning space application popularization activity and the special training advanced seminar and work deployment meeting of "Online Learning Space for Everyone" were held. After selection and investigation by experts, 26 special training base schools of "Online Learning Space for Everyone" were identified in 2019. In Hefei, Anhui Province and Tangshan, Hebei Province, the special training of "Online Learning Space for Everyone" was held for primary and secondary school principals, training 453 people; In Shijiazhuang, Hebei Province, Zoucheng, Shandong Province, and Wuhu, Anhui Province, the special training of "Online Learning Space for Everyone" was held, training 746 people.

　　Public service system of educational resources By the end of November, the national public service platform for educational resources had opened 13.37 million spaces for teachers, 6.27 million spaces for students, 5.84 million spaces for parents and 400,000 spaces for schools. Continue to promote the access of pilot regional platforms to the national public service system of digital education resources. 112 online platforms at all levels have been connected, including 1 national platform, 26 provincial platforms, 44 municipal platforms and 41 district and county platforms. According to the new access standards, 124 applications from 61 units have been connected. The public service system has a total of 825,000 space logins, 42.48 million monthly users and 41.65 million application visits.

　　Informatization of educational management (omitted)

　　Integration and sharing of government information system The Ministry of Education has approved five interface applications from the Ministry of Justice on the information of college students’ status, academic qualifications, degrees and studying abroad, which are used for information verification in the legal professional qualification examination.

　　Pilot demonstration of educational informatization The Science and Technology Department of the Ministry of Education has deployed and launched the project recommendation and selection of the application community of educational informatization teaching in 2019, and plans to select about 15 practice communities with different application directions from four modes, including online learning space, online open courses, interdisciplinary learning (STEAM education) and intelligent education.

　　Educational informatization propaganda The briefing column of the Ministry of Education published "Accelerating the construction of special education network in Jiangxi Province to promote the inclusive sharing of high-quality educational resources" and "Deepening the construction of educational informatization in xidian university to promote the upgrading of educational management". China Education News compiled and distributed two special issues of informatization, and published articles such as "Creating China Road for Online Education" and "Guiyang: Popularizing Artificial Intelligence Education". China Education News Network published 39 reports related to informatization, and China Education TV broadcasted 25 main reports related to educational informatization through National Education News Network.

　　★Progress in Key Work of Network Security

　　Network security incident handling (omitted)

　　Information system security monitoring (omitted)

　　★Related work information

　　People-taught digital teaching materials Complete the updating of 10 basic versions of textbooks in Chinese, Morality and Rule of Law and History, and the updating of 3 complete versions in Chinese and History, including 791 audio, 148 pictures, 45 animations and 311 videos.

　　Special research on educational network security work On October 30-31, the "2019 Education Network Security Seminar" sponsored by the Education Management Information Center of the Ministry of Education and co-organized by the Jiangsu Provincial Department of Education and Huawei Technologies Co., Ltd. was held in Nanjing, attended by more than 600 principal responsible comrades from local education administrative departments and technical support departments of network security and informatization construction in colleges and universities.

　　★Work trends in various places

　　Beijing The Municipal Education Commission completed the acceptance of the education informatization project in 2019, and organized the pre-financial performance evaluation of the education informatization project in 2020; The list of "Double Hundred" demonstration projects of Beijing’s educational informatization integration and innovation in 2019 was announced.

　　Tianjin On November 29th, the Municipal Education Commission and Iflytek Co., Ltd. signed a strategic cooperation agreement to jointly build a networked, intelligent and personalized precision learning system.

　　Hebei On November 21-24, the expert work meeting of the comprehensive reform pilot project of "National Training Plan (2020)" in Hebei Province was held in Shijiazhuang.

　　Shanxi On November 4-9, the advanced seminar on professional ability of Shanxi education informatization was held in Chengdu. The Provincial Department of Education launched the pilot project of "Jinxiangyun Classroom" to help the poor through the internet. Linfen No.1 Middle School, fangshan county Jicui Demonstration Primary School, Zuoquan Matian Central School and kelan county Taoyuan Sheng Experimental Primary School were selected as the first batch of pilot schools to explore the application mode of informatization in education precision poverty alleviation.

　　Liaoning (Province) The Provincial Department of Education released the results of the 23rd Education and Teaching Informationization Competition in Liaoning Province, and issued the Notice on Continuing the Popularization of Online Learning Space Applications. The Provincial Audio-visual Education Center went to Jinzhou, Liaoyang and Chaoyang to carry out educational informatization education and training activities.

　　Jilin (Province) The Tenth Five-Year Plan of Education Informatization in Jilin Province has been included in the catalogue of provincial special planning in the Tenth Five-Year Plan of Jilin Province. On November 22nd, the Provincial Department of Education issued the Notice on Doing a Good Job in Investigating the Development of Education Informatization in 2019. The Provincial Department of Education held a training on the application of national education informatization management information system in Jilin University, with more than 90 system administrators and auditors attending.

　　Heilongjiang Province The Provincial Department of Education organized a special training on "National Education Informatization Management Information System", with more than 260 participants.

　　Zhejiang(Province) The Provincial Department of Education issued the Notice on Doing a Good Job in Recommending and Selecting the Experimental Zone of "New Teaching and Learning Mode Based on Teaching Reform and Integrating Information Technology", announced the provincial-level "excellent courses" list of "One Teacher, One Teacher" activities in 2019, the results of the excellent space collection activities, and the recruitment results of the film and television resources collection activities in primary and secondary schools, and started the identification of the first batch of robot teaching demonstration schools. On November 28-29, in 2019, the information technology application innovation competition for primary and secondary school teachers in the province was successfully held.

　　Anhui (Province) In 2019, the smart school construction project of small-scale compulsory education schools (teaching points) in poverty-stricken areas was publicly invited for bidding in Hefei Public Resource Trading Center, Anhui Province, and the winning bidders in each package of the project were determined.

　　Fujian(Province) The Provincial Department of Education issued the Emergency Plan for Cyber Security Incidents in Fujian Education System and the Process of Reporting and Handling Cyber Security Incidents in Fujian Education Department, and announced the online and offline hybrid courses of provincial-level quality products in 2019 and the application-oriented undergraduate teaching team in massive open online course.

　　Jiangxi The Provincial Department of Education issued the "Implementation Plan for Training All Employees in the Application of" Ganjiaoyun. Teaching Pass 2.0 "; Actively participate in the 2019 cyber security emergency drill organized by the Network Information Office of the Provincial Party Committee, and organize the 2019 special training on cyber security of the province’s education system in two phases. In 2019, the evaluation of smart campus construction in colleges and universities and the preliminary contest of the second Jiangxi University Network Security Skills Competition were successfully completed.

　　Shandong(Province) On November 22nd, 2019, the off-line on-the-spot meeting of the provincial workshop on biology in junior high school of internet plus Teachers’ Professional Development Project was held in Guangrao Experimental Middle School, Dongying City.

　　Henan(Province) Start the implementation of the second batch of educational informatization 2.0 demonstration zones, and organize the on-site review of digital campus benchmarking schools in primary and secondary schools.

　　Hunan On November 6th, the first Xiangjiang Forum of Education Think Tank was held in Changsha. On November 15th, My People，My Country, the first class of "I am the successor", was officially started. The Provincial Department of Education completed the mid-term evaluation of 100 million engineering projects in Hunan Province, and launched the popularization activities of online learning space application in Hunan Province in 2019.

　　Guangxi The Education Department of the Autonomous Region held the demonstration and observation activities of excellent lessons in the deep integration of information technology and subject teaching in primary and secondary schools in the whole region, the network security training meeting of the education system in the whole region and the implementation meeting of equal insurance 2.0; Successfully completed the activity of "one excellent class for one teacher and one famous teacher for one class" and awarded 600 excellent classes at the autonomous region level.

　　Hainan On November 28th, the Party Committee of the Provincial Department of Education concentrated on conveying and studying the spirit of the important instructions of the Supreme Leader General Secretary on the "Four Persistences" in national network security work, and informed the situation of the offensive and defensive drills of the province’s education system in the "Network Protection Action".

　　Chongqing On November 23rd, the Municipal Education Commission issued the Notice on Carrying out the Investigation on the Development of Education Informatization in 2019. On November 15th, the city’s education network security training meeting was held in Jiangbei District.

　　Sichuan(Province) The Provincial Department of Education organized the official opening ceremony of the "Sichuan Yunjiao" live classroom; Organize the online evaluation of provincial-level "excellent courses" in the activity of "one teacher, one excellent course and one famous teacher" in 2019, print and distribute the file of "classroom teaching contest" in autumn 2019, and start the autumn drying class.

　　Guizhou (Province) The Provincial Department of Education carried out the provincial-level evaluation and ministerial-level evaluation and recommendation of "one excellent course for one teacher and one famous teacher for one lesson", and reviewed 2289 sections of provincial-level "excellent courses"; Organize a special training meeting for the popularization of online learning space application in the whole province.

　　Yunnan(Province) The Provincial Department of Education carried out online learning space training for teachers in primary and secondary schools and high schools in the province, and carried out training, teaching and research, evaluation and other activities for more than 360,000 teachers covering primary and secondary schools and high schools through online learning space.

　　Xizang The Education Department of the Autonomous Region issued the "Notice on Further Promoting the Networking of Primary and Secondary Schools" to comprehensively promote the improvement of school network access and bandwidth conditions.

　　Shanxi(Province) On November 1, the Provincial Department of Education organized a conference on network security and informatization in colleges and universities in Shaanxi Province; On November 2 nd, organize an exchange meeting on the deep application of virtual reality in teaching; On November 8-10, organized the Shaanxi Education Informatization Innovation and Development Conference.

　　Gansu On November 6-19, the Network Information Committee of the Provincial Education Department conducted an on-site inspection of the network security work of 10 universities including Northwest Normal University. Gansu Audio-visual Education Center organized experts to conduct provincial-level acceptance of the provincial-level information demonstration project of "sharing quality education resources in big cities" in Qingyang and other places in 2018.

　　Qinghai On November 17-24, a training course for information management team in Qinghai Province was held in Chengdu, Sichuan, with 95 participants.

　　Ningxia The Education Department of the Autonomous Region has compiled the Work Project Plan for Improving Weak Links in Compulsory Education in the Autonomous Region (2019-2020), and organized the popularization and application activities of online learning space applications in 2019; On November 5-6, the "internet plus Vocational Education" observation and vocational education reform and development training meeting was held; On November 20-22, a special training and offensive and defensive drill contest on cyber security in education industry was held.

　　Xinjiang The Education Department of the Autonomous Region has adjusted the leading group for network security and informatization, and established three groups, namely, the school Internet Party building working group, the informatization promotion group and the network security supervision and inspection group.

　　Xinjiang production and construction corps The Education Bureau of the Corps issued "Guidelines for the Construction of Digital Campus Application Centers in Primary and Secondary Schools of the Corps (Trial)". The Education Management Information Center of the Corps organized a mid-term construction evaluation of the public service platform of educational resources of the Corps.

　　Cctv newsA kind of crystal mud toy called "slime" is popular among students now. This kind of jelly-like crystal mud is soft and elastic and can be kneaded into various shapes. However, the raw materials of crystal mud sold by many merchants contain borax, which is a toxic and harmful substance that will cause certain harm to children’s health. However, the reporter’s investigation found that this kind of bright-looking but harmful "crystal mud" toy is popular both online and offline.

　　The reporter searched the shopping website for "slime" crystal mud, and found that there are thousands of shops selling this kind of toy. The price ranges from several yuan to several tens of yuan, and the production package containing more materials is as high as several hundred yuan. The website also comes with detailed graphic introduction and video tutorial. The reporter found that the sales volume of these "slime Crystal Mud" is very considerable, and some shops have thousands of monthly sales.

　　Online sales are so hot, is offline sales equally popular? The reporter visited the stationery stores around some schools in Nanning, Guangxi, and a large number of "three noes" and "slime" crystal mud without the name of the manufacturer, the date of production and the logo of the production license were placed on the commodity shelves in an imposing manner. In this stationery store, the reporter found boxes of slime crystal mud for sale. In this box of crystal mud, there are a bottle of special glue for crystal mud, a bottle of borax water, pigments, stirring rods and other corresponding tools.

　　In addition to selling this kind of crystal mud, some stationery stores are still selling crystal mud products.

　　For the borax component in the "crystal mud", the clerk claimed that he had long been accustomed to it.

　　Borax has high toxicity, long-term contact or poisoning.

　　Because the crystal mud contains the poison "borax", parents are worried that it will do harm to their children’s health. So, how toxic is borax? What is its harm to children?

　　Borax, as a very important boron-containing mineral and boron compound, has a wide range of uses, which can be used as cleaning agents, cosmetics and pesticides. In medicine, borax can also be used for disinfection and antisepsis of skin mucosa, treatment of pulpitis and epilepsy.

Jiang Xia, Chief Pharmacist of Pharmacy Department of the First Affiliated Hospital of Guangxi Medical University

　　Jiang Xia, Chief Pharmacist of Pharmacy Department of the First Affiliated Hospital of Guangxi Medical University:Borax, as a mineral Chinese medicine, is mainly used for external use, but the dosage is not large, such as some eye drops and some powders, but the dosage is not large. The use time should not be too long, and the poisoning reaction is mainly due to the accidental intake of a large amount of borax or long-term contact.

　　It is precisely because of the high toxicity of borax that eating food with borax may cause cumulative damage to human body, so China’s Food Hygiene Law and Food Additives Hygiene Management Measures explicitly prohibit the use of borax as a food additive. Then, will toys made of borax be harmful to children?

　　Chen Cheng, Law Enforcement Officer of Chongqing Kaizhou District Industrial and Commercial BranchAfter playing with borax, children don’t pay special attention to hygiene. It is possible that borax will be quickly absorbed by the human body from the wounds on their mouths or hands, and then symptoms such as poisoning, vomiting and diarrhea will be formed in children, which will seriously cause shock and even affect life safety.

　　Borax is not easy to metabolize and accumulate seriously in the body or cause death.

　　According to the doctor, borax will be absorbed by the human body quickly, but the process of metabolism from the body is slow. Long-term accumulation in the body will lead to indigestion in children, and in severe cases, it will be life-threatening. In addition, children often contact crystal mud with borax, and some skin allergic reactions will occur. Although skin absorption is much slower than food absorption, the consequences can not be underestimated.

　　Jiang Xia, Chief Pharmacist of Pharmacy Department of the First Affiliated Hospital of Guangxi Medical UniversityAfter such contact for a long time, it is possible that borax will be absorbed into the body through the skin, which will cause certain accumulation in the body, because borax is not easy to excrete in the body, which may trigger a series of toxic reactions; In severe cases, there will be some symptoms of the nervous system. In severe cases, there will be coma, shock, and even circulatory failure, which will lead to death.

　　Check the harmful "crystal mud" goods and ban them.

　　Parents’ worries are not groundless. In view of the harm caused by "slime" crystal mud, recently, many districts and counties in Chongqing have launched a campaign to check the harmful "crystal mud" within their jurisdiction.

　　On March 28th and 29th, the multi-departments of Yongchuan District and Kaizhou District of Chongqing jointly enforced the law, and launched a special campaign to check the "crystal mud" in their respective areas, pulling nets to check the small shops, wholesale and retail outlets around some schools in the city, and seized more than 1,400 boxes of crystal mud. The reporter followed the law enforcement officers in Kaizhou District to see in a stationery store around a school that "crystal mud" was placed in a conspicuous place in the container. Law enforcement officers immediately ordered him to take the goods off the shelf and warned the merchants not to sell the goods.

　　Judging from the seized products, these "crystal mud" belong to "three noes" products, and law enforcement officers seized these products.

　　Chen Cheng, Law Enforcement Officer of Chongqing Kaizhou District Industrial and Commercial BranchWe seal up the products seized today, and then rely on qualified inspection units to carry out inspection. If we do find any product quality problems, we will deal with them according to the Product Quality Law.

　　Law enforcement officials said that the next step will be to carry out continuous inspections in stationery wholesale markets, shops around schools and rural schools.

　　Ruan Zaichun, captain of the law enforcement detachment of the Kaizhou District Industrial and Commercial Branch of Chongqing: For businesses that are still selling crystal mud, they should stop selling and immediately take them off the shelves. We will further strengthen inspections in the future and resolutely investigate and deal with them when they are found together.

　　Here, we should also remind parents to buy toys for their children. Never buy such "three noes" crystal mud, borax water and borax powder, and don’t let poisonous toys become potential "child killers". At the same time, it is also hoped that relevant departments will strengthen supervision, standardize the production of related enterprises from the source, and make children’s toys safer.

　　01

　　Recent or aggravated chest tightness

　　If the chest tightness after exercise suddenly appears recently, it can be relieved after rest, suggesting that you may have coronary heart disease.

　　If you have symptoms of chest tightness before, and the symptoms are aggravated recently, it means that the previously stable plaque may develop into large damage at any time, leading to the occurrence of acute myocardial infarction.

　　02

　　palpitations

　　Irregular increase in heart rate is usually the result of tachyarrhythmia.

　　Most arrhythmias are less dangerous and will not cause sudden death, but if they are frequent ventricular arrhythmias, there is a risk of developing ventricular fibrillation.

　　03

　　bradycardia

　　The beating of the heart is initiated by specific pacing cells. If the function of pacing cells becomes worse, the beating rate of the heart will be slowed down, and in severe cases, cardiac arrest will be caused.

　　When the heart rate is less than 50 times, the blood pressure becomes low, which is prone to long-term cardiac arrest, leading to sudden death.

　　04

　　faint

　　Syncope is an important precursor of sudden death. Most syncope is caused by the sudden slowdown or stop of the heartbeat, resulting in insufficient blood supply to the brain.

　　Sometimes syncope can recover after a few seconds, and if it can’t recover, it will cause sudden death. In case of unexplained syncope, you should be very vigilant and find out the reason as soon as possible.

　　05

　　Unexplained fatigue

　　Unexplained fatigue and fatigue, or accompanied by chest tightness and edema, should be alert to sudden death, which may be caused by myocarditis or cardiomyopathy.

　　Myocarditis is more common among young people, usually after 1~2 weeks of catching a cold, with symptoms such as fatigue, chest tightness and fatigue, which can easily cause acute heart failure. In this case, heavy physical activity and bed rest should be strictly prohibited.

　　06

　　Black eyes and numbness of limbs

　　Stroke is also an important cause of sudden death. If you can’t see things on one side, your limbs are numb and weak, or you walk unsteadily and feel like stepping on cotton, you should be alert to the occurrence of stroke.

　　Special tips

　　The golden emergency time of sudden death is within 10 minutes of onset.

　　Once the people around you have cardiac arrest,

　　Call 120 for help quickly.

　　You can do this in addition to dialing 120.

　　Hand-held cardiopulmonary resuscitation

　　Left hand, right hand, straight hand on your heart.

　　Depth, depth, depth of 5CM

　　Speed, speed, speed twice a second

　　And don’t let it stop

　　▽

　　Ask AED "life-saving artifact" for help!

　　AED is also called "stupid defibrillator"

　　There is a voice prompt operation throughout the process.

　　A few simple steps, "fool" can learn.

　　▽

　　For cardiac arrest

　　Use AED to cooperate with electric shock defibrillation

　　The success rate is as high as 90%

　　It is reported that timely defibrillation is the most effective way to stop sudden cardiac death.

　　Within 3 minutes of the patient’s cardiac arrest, the patient was quickly defibrillated by electric shock, and the success rate of defibrillation was as high as 94% only once.

　　How to use the AED?

　　Don’t worry, look down.

　　AED is a "stupid machine", which will automatically identify abnormal heart rhythm that needs electric shock and give it electric shock. There are only four simple steps to use: starting-connecting-discharging-defibrillation.

　　Sticking electrode sheet

　　▽

　　Do not touch, analyze the heart rhythm and give defibrillation.

　　▽

　　Special reminder:

　　① Follow the diagram to start the machine.

　　② Stick the electrode pad and plug it in. The voice prompts that the heart rhythm is being analyzed. Please do not touch the patient.

　　After the AED is turned on, it can never be turned off, which has nothing to do with whether the patient is saved! You can’t turn it off if you save life! Only when the professional medical personnel arrive and replace the AED with a manual defibrillator can the electrode pads of the AED be removed.

　　There are too many registered people and the queue time is long? You can register before going out; The hospital is too big? Unable to find the target department? Hospital map navigation can appear when the mobile phone is "shaken"; Unattended in hospital? The intelligent mattress of sickbed helps to monitor whether it is necessary to turn over at night; Legs and feet are inconvenient, so you can’t go to the canteen to eat? One-click inquiry and ordering of suggestions for feeding meals, details of medication, progress of illness and matters needing attention in the bedside pad of the ward … …

　　With the rapid development of information technology, big data and artificial intelligence, it seems that many lifestyles are changing, and smart hospitals are quietly sprouting. Recently, 2019 Shenzhen Shanghai Smart Hospital Construction and Operation Seminar was held, and experts from all over the country made suggestions and suggestions for smart hospitals. Previously, the National Health and Wellness Committee held a press conference on "Informatization Quality Control and Smart Hospital Construction" in Beijing Tiantan Hospital. The reporter personally experienced the medical changes brought about by informationization and intelligence.

　　Meet black technology in the door

　　"The scope of smart hospitals mainly includes three major areas: &lsquo for medical staff; Smart medical care ’ , mainly based on electronic medical records as the core of information construction; Patient-oriented ‘ Smart service ’ , such as mobile phone settlement, appointment registration, appointment diagnosis and treatment, parking information push, etc.; Hospital management oriented ‘ Smart management ’ That is, to achieve refined and information management. " Jiao Yahui, deputy director of National Health Commission Medical Administration and Hospital Authority, said.

　　For patients, in addition to the effect of diagnosis and treatment, what is important is the medical experience. "From entering the gate of Tiantan Hospital, I met all kinds of ‘ Black technology ’ 。” Zhou Jianxin, vice president of Tiantan Hospital, introduced the situation of "self-service" to the reporter. "The outpatient service is self-service in the whole process, from purchasing the case book to registering and taking the number, to seeing a doctor, checking and printing the report, to taking medicine and printing the invoice. The patient only needs to scan the code on various machines, and the system will automatically make an appointment for the patient, just waiting for the machine to call the number at the corresponding place, basically bidding farewell to the long queue in the past."

　　In the lobby of the hospital, the reporter saw a number of intelligent consultation machines. From time to time, patients or their relatives inquired about outpatient pharmacies, hospital fees, inspections and other information in front of the consultation machines. The distribution points of convenience facilities such as gates, drinking places and elevators were also very clear. Take out your mobile phone next to the consultation machine and "shake it". The intelligent navigation system covering the whole hospital can automatically plan the appropriate route, and the accuracy is calculated in meters.

　　In order to meet the needs of patients for continuous medical treatment, Tiantan Hospital has also added the function of "one-click follow-up". The patient can select the option of "Follow-up Registration" in the "Registration" interface of the mobile phone "Beijing Medical Link", so that he can see the previous medical records and directly make a "point-to-point" appointment for the last deputy director and above.

　　In addition to consultation machines and registered self-service machines, sharing wheelchairs is also very popular. "It’s very convenient and cheap, and it’s free to use for the first 3 hours every day." Mr. Wang, who "borrowed" a shared wheelchair, was full of praise for this.

　　In the corridor of the inpatient department, rows of cabinets like express self-service cabinets constitute the clothing self-service recycling station. Zack Zhang, director of the outpatient department of Tiantan Hospital, said that the clothes in each ward were collected for cleaning or related treatment.

　　Self-help facilities can not only provide auxiliary medical services, but also save lives in an emergency. Zack Zhang introduced that Tiantan Hospital has set up more than 90 automatic external defibrillators, so that patients in critical condition can get basic cardiac rescue measures as soon as they enter the door, which saves the time of pushing into the emergency room. "For saving people, every minute and every second is robbed."

　　Wards can also be highly intelligent.

　　"This thing is powerful, it can order food on it, and it can be evaluated by doctors and nurses, as well as medical science." Inpatient Mr. Zhao pointed to the "suspended" pad with adjustable bedside distance and told the Science and Technology Daily reporter. These are some explorations made by Tiantan Hospital in the construction of intelligent wards.

　　"In our ward, every patient has a pad at the bedside. This bedside interactive system of smart ward can not only provide entertainment functions such as digital TV for inpatients, but also enable patients to query their medical records, make appointments, order nutritious meals and so on in real time." Zhou Jianxin said.

　　In Mr. Zhao’s hospital bed, the humble mattress also has "high intelligence". According to Bai Bo, deputy director of Tiantan Hospital Information Center, the smart mattress has a built-in chip, which can wirelessly transmit the collected information of patients’ physical condition to the monitoring platform, and monitor patients’ vital signs in real time. Once patients leave the bed for too long, the nurse station will immediately call the police to prevent accidents such as falling and fainting.

　　Not only that, the hospital can also display the patient’s doctor’s orders, the progress of infusion, medication reminders and other information on the big screen of the nurse station in real time, so that family members and patients don’t have to look up at the infusion set from time to time. On the big screen of the nurse station in Ward 3 of Vascular Neurology, the reporter saw that it clearly showed the real-time dynamics of infusion of more than 30 patients, and the patient numbers with less dosage and too fast infusion were automatically marked with different colors. "The infusion monitoring system has reduced a lot of burdens for patients’ families and medical staff. We can plan a scientific and time-saving route according to the screen display to ensure the safety of infusion and medication for every patient. " A nurse told the Science and Technology Daily reporter.

　　"At present, there are about 200 such smart beds in the whole hospital, which are distributed in various wards." Bai Bo said that such a smart sickbed is not expensive, and every patient has the opportunity to enjoy such a smart sickbed, just like the ordinary sickroom.

　　Zhou Jianxin said that in addition to the smart ward, the hospital has also explored many "high intelligence" technologies applied to medical practice. For example, BioMind, the world’s first neuroimaging artificial intelligence aided diagnosis product, can be used in 3-mdash; Automatically write a structured diagnosis report within 5 seconds; There are also intravascular interventional surgical robots, bone wearing robots and medical AI robots, which can be developed and transformed soon.

　　Consultation breaks through long distance

　　If smart hospitals such as self-help and smart wards are regarded as a point, remote consultation may connect points all over the country or even around the world into a line and radiate into a plane.

　　"Patients no longer seek medical treatment everywhere, but ‘ Foot-out area ’ You can enjoy the diagnosis and treatment services of national experts. " Li Liang, vice president of Beijing Chest Hospital, said that telemedicine can not only save patients from the pain of travel, but also enjoy better medical resources. More importantly, it can prevent infectious patients such as tuberculosis from causing a wider range of infections on the way to seek medical advice, thus achieving the purpose of effective prevention and control of infectious diseases. Not long ago, Beijing Chest Hospital and other units jointly set up a hospital-linked remote diagnosis and treatment platform, and set up a green channel for diagnosis and treatment between Beijing Chest Hospital and various tuberculosis prevention and treatment institutes in Beijing.

　　In the remote consultation room of Beijing Chest Hospital, the reporter of Science and Technology Daily observed the remote diagnosis and treatment process of a pulmonary tuberculosis patient admitted by Daxing District Tuberculosis Control Institute in Beijing. Doctors from Daxing District Institute of Tuberculosis and Prevention briefly introduced the patient’s condition and medication through high-definition video, and the patient’s detection image data were also transmitted simultaneously. Three experts from Beijing Chest Hospital asked and discussed from time to time, and finally determined a scientific, reasonable and feasible treatment plan.

　　"When necessary, the patient himself will ‘ Appear ’ So that we can know the condition more accurately and comprehensively. " Gao Mengqiu, director of the Second Department of Tuberculosis, Beijing Chest Hospital, told the Science and Technology Daily reporter.

　　The earliest remote consultation may only start with a mobile phone that can shoot videos. Now the relevant state departments attach great importance to the construction of high-quality telemedicine.

　　"This year, we will carry out pilot projects for the construction of urban medical groups in one hundred cities, and apply ‘ Internet plus & rsquo; Methods The telemedicine system, tele-consultation system, tele-education system and two-way referral system supported by informatization were established in the medical association, and the information interconnection, intercommunication and sharing of patients from primary medical institutions to superior hospitals were explored. The medical association will provide patients with continuous and integrated diagnosis and treatment services. " Jiao Yahui said.

　　"Overall, the development of China’s medical services is in the process of changing from ‘ Informatization ’ To ‘ Wisdom ’ The critical stage of the transition. " Jiao Yahui said. The wisdom hospital is on the road, or not far away.

"Congratulations on lending 500,000 yuan, and customers can’t keep up." Xiao Bo (a pseudonym), who claimed to be an intelligent outbound service provider for telemarketing, updated his circle of friends with a screenshot of a customer’s successful lending. In Xiao Bo’s circle of friends, there are many similar "success stories". Xiao Bo claims that his telemarketing robot can make more than 1,000 calls in a single day, and the connection rate remains at 30% or even higher, and can avoid supervision and prevent titles.

Are you still bothered by harassing calls about selling loans and POS machines?

From late October to November, 2021, The Paper reporter found that the chaos in the telemarketing industry still exists. The technical model of "outbound call system+telemarketing robot" claims to be able to accurately dial the special line and mark the customer information, and evade the supervision of communication operators through technology; Behind it are hidden behaviors such as illegal trading of personal information and illegal sales of POS machines.

The so-called "anti-sealing" call-out system for electric sales

Telemarketing is a sales method relying on telephone, which contacts customers through special telephone marketing numbers to complete product promotion, quotation, transaction, etc., but this method is often easy to cause harassment to users. In the media reports, there are many cases in which telephone users are often disturbed by receiving telemarketing calls. In recent years, the Ministry of Industry and Information Technology and the three major operators have taken measures such as "high-frequency call blocking". However, with the application of intelligent voice and other technologies, the intelligent outbound calling software system, which claims to be able to make a large number of calls a day and "prevent blocking" (prevent blocking), still makes users hard to prevent.

A recent survey in The Paper found that some telemarketing software used "anti-sealing" as a gimmick to attract customers, and all kinds of "anti-sealing robots" gradually became popular in the market.

In Baidu Post Bar and Tencent QQ, the keyword "electricity sales" is searched, which shows a lot of information about "electricity sales software". The reporter randomly joined a QQ group named "Outbound Call System for Telemarketing", with more than 1,000 members and an account named "Chamber of Commerce for Telemarketing Systems" posting various promotional information related to Telemarketing from time to time in the group. "electricity sales card", "electricity sales App" and "electricity sales anti-sealing system" ……

The sales information in the group claims that the services provided can cover the whole industry such as finance, collection, loan, insurance, health care, drinks, auto insurance and games.

The reporter randomly added the WeChat of Xiao Bo, a telemarketing intelligent outbound service provider, from the QQ group. He asked the reporter what business he wanted to do, saying, "Let’s see if we can do it. Now the telecom fraud investigation is strict." After confirming that it was a "campus loan" business, he enthusiastically introduced his products and sent a price list, including a set of real-life speech made by 300 yuan, and a robot package divided into basic version, premium version and agent version according to different price points and specifications. During the conversation, Xiao Bo said that most of his clients are selling financial stocks, loan insurance and POS machine sales, all of which can be "sealed".

In his description, the "anti-sealing robot" does not need any calling cards and auxiliary equipment, and the outbound call system purchased together will use the group call line to dial the number. Regarding the reporter’s question that "making too many calls will not be seized", Xiao Bo replied that a certain line will inevitably have complaints every month, but as long as it reaches the upper limit of the complaint rate, it will stop the line and replace it with another one, so as to prevent the system purchased by customers from being blocked. He also mentioned a new business to be launched soon-an anti-sealing App for electricity sales. In the promotional picture of the App, the words "the three major operators’ Puka seconds turn white list and the high frequency does not seal the number" are placed in the most conspicuous position.

In order to further dispel the reporter’s doubts, Xiao Bo added, "We are first-class landing line operators and all cooperate with operators."

He Zheng (a pseudonym), another service provider who claimed to be engaged in the research and development of the telemarketing system for 6 years, explained to reporters that the telemarketing robot business on the market now basically adopts the "line+system+service" model. Buyers only need to use the account they provide, and they can enjoy a full set of services, "including technical support, carrying lines and after-sales."

In the 1 minute and 22 second recording of "Loan Talk" he sent, a customer on the other end of the phone in love women, who claimed to be a "customer service representative of a bank", indicated that he could handle a loan of 3-5 million yuan and "pay it back as you borrow it". In this conversation, the customer service representative repeatedly said that he was a staff member of "a bank credit center" and asked about the occupation of the telemarketing customer, the loan and insurance business he handled, and "whether there is a house or a car under his name".

He Zheng said that the so-called "bank customer service representative" bought their telemarketing system, recorded it in advance, and combined it into a complete sales talk according to the matching of the system. The customer thought it was a real person and was constantly "promoted", and might place a loan order. But in fact, they don’t know whether this "bank customer service representative" is a bank staff member or a telecom fraudster.

The "material dealer" in the dark of the electricity sales industry

In the telemarketing industry, an important part is to obtain customer information resources. The illegal trading of personal information also breeds in the dark.

After the reporter joined a QQ group, a "supplier" who claimed to specialize in health care lines (the person who provided information such as the user’s phone number) sent a message in the QQ group saying that he obtained the information of consumers who bought a health care book in TV shopping programs and then sold it to the telemarketing team or system service provider who promoted health care products. In the screenshots he sent, these consumers are distributed in different provinces such as Shandong, Henan and Zhejiang.

Compared with system service providers, "material suppliers" are more cautious. They usually don’t directly give contact information such as WeChat or telephone, and they will communicate further after confirming that the other party is an "intended customer".

In a chat with a "supplier" named AZY, the reporter learned that most customer resources are divided into "AI materials" and "hand-stripping materials". "AI material" is provided for electric sales robots, while "hand stripping material" is provided for employees who make phone calls manually. According to the feedback rate of dialing, the prices of the two "materials" are also different. Generally speaking, the feedback rate of "hand stripping" is higher than that of "AI material" and therefore the price is higher.

According to the price standard sent by AZY, 600 yuan RMB can buy 10,000 pieces of AI materials or 1,000 pieces of user information. These materials are usually replaced by different pinyin abbreviations, such as the special line for investors, which they call "GM powder", and the online loan, which is called "Wd".

There are many "anti-pit and anti-second-hand material merchants" posts in Baidu Post Bar. Some familiar "material merchants" will add WeChat to each other and set up their own WeChat groups, in order to expand or stabilize their sources of "materials".

In the investigation, the reporter found that in order to be more concealed, the transactions between suppliers and buyers often shift from WeChat to other more private online trading platforms. The line operator "AXY" chose an overseas chat software called "Telegram" to complete the transaction with the customer. After failing to reach a transaction with the reporter, "AXY" immediately closed his QQ space.

How to deal with the chaos of electricity sales

In recent years, the phenomenon of electricity sales has been repeatedly concerned and rectified.

In 2019, the central bank issued document [2019] No.85 "Notice of the People’s Bank of China on Further Strengthening the Management of Payment and Settlement to Prevent New Crimes in Telecommunication Networks", pointing to the chaos of telephone sales of POS machines. At the same time, a number of payment institutions issued a notice on strictly prohibiting online sales and electronic sales of POS machines. However, the circle of friends of service provider He Zheng is still full of sales records of a large number of "POS machine" sales customers. When the reporter asked about the POS machine sales business, he did not show him any business license in the financial industry.

According to media reports, the sales scam of POS machines has already become a high-incidence area for complaints. Telephone sales mostly attract customers to use their products with "low rate and free delivery", but after the user places an order, there will be various charges including activation fee, deposit, service fee and so on. The reporter’s search on the Internet also found that many deceived users reported that they could not get the account after receiving the POS machine, and even were blacked out directly by the salesman.

In May this year, the Consumer Protection Bureau of China Banking and Insurance Regulatory Commission issued Circular No.8 of 2021, "Circular on Cases of Ping An Bank’s Telemarketing of Physical Products Infringed on Consumers’ Legal Rights and Interests" (hereinafter referred to as "Circular"), which informed the case that Ping An Bank cooperated with a third party to sell physical products by telephone and infringed on consumers’ legal rights and interests.

According to the "Circular", in the spot check of 60 physical products sold by Ping An Bank Credit Card Center, 53 businesses were illegal, accounting for 88.33%.

Fu Liang, a telecom analyst, told The Paper that at present, the management of the domestic electricity sales industry has not yet formed a complete norm. "Many links have not been (completely) opened." If the management standards between relevant departments cannot be unified, there will be barriers to the management and rectification of the chaos of electricity sales. Even if users find their personal information leaked or traded, it is often difficult to find a "channel" for complaints and handling.

Fu Liang also pointed out that operators are the primary link to ensure that users’ information is not leaked. They often have their own strict operating norms, but they cannot completely avoid the possibility of leaks in huge business branches. Moreover, in this highly developed network era, many personal information is in a "semi-public" state.

He believes that in the use of various scenes in daily life, such as telephone numbers and names, information is constantly used and exchanged, and it is difficult to completely quantify whether it involves "privacy disclosure". "If there is an improper transaction of user information, no matter where it happens, it is an illegal act."

　　Knowing the news of Huang Xing’s death, Yang Chengrong, a poor household who was nearly 80 years old, burst into tears: "He is a relative of our poor household!"

　　Huang Xing, deputy director of Shiyan Poverty Alleviation Office, Hubei Province. On February 28th this year, 46-year-old Huang Xing suffered a sudden myocardial infarction after working for several days in a row. He died in the line of duty and fell on the road to poverty alleviation. Recently, the Hubei Provincial Federation of Trade Unions posthumously awarded Huang Xing the Hubei May 1 Labor Medal and called on the majority of trade union cadres to learn from it.

　　I broke down from overwork and had a heart attack. I went to the hospital with a poverty alleviation manual.

　　Shiyan Poverty Alleviation Office, Office 4128. The large-scale schematic diagram of the Ten Commandments’ accurate poverty alleviation is still hung in a prominent position on the wall, but it can’t wait to draw its owner.

　　"He misses the poverty alleviation work every day and always refuses to let himself take a short rest. This time he can finally rest." Xu Hongbo, the chief of general department in the same office as Huang Xing, wiped away tears and said.

　　In the last 59 days of his life, except for the four-day holiday of the Spring Festival, Huang Xing has been running in the front line of poverty alleviation, including 23 days in northern Shaanxi to participate in the inter-provincial cross-examination of national poverty alleviation and development.

　　"In northern Shaanxi, there is ice and snow everywhere, and it is about MINUS 20 degrees Celsius outside. Huang Xing enters the village during the day, and he has to work overtime after the group meeting at night, often after 2 am." Zhang Guangming, deputy director of the Poverty Alleviation Office in Maojian District, Shiyan City, Hubei Province, who participated in the assessment with Huang Xing, said that as the deputy head of the assessment team, Huang Xing was not only responsible for routine work, but also responsible for overall planning and summary, which was more arduous than the work of the team members.

　　Returning to Shiyan from Shaanxi, Huang Xing neglected to rest and continued to work overtime.

　　"On February 26, two days before his illness, he was still supervising the poverty alleviation assessment in danjiangkou city." Xu Hongbo recalled that on February 27th, Huang Xing came to the office early and worked overtime until about 11 o’clock that evening. Suddenly, he said that his heart was uncomfortable, and Xu Hongbo and his colleagues rushed him to the hospital.

　　When he went to the hospital, he still had a poverty alleviation manual in his pocket. Xu Hongbo said that in the last few hours of his life, Huang Xing was still asking the doctor: "Can you give me some medicine? I want to go back to work early."

　　Due to his serious illness, Huang Xing was still unable to recover his vital signs after being rescued in the intensive care unit for more than 10 hours. He died at noon on February 28th at the age of 46. His family left only his 80-year-old frail mother and his daughter who was in the first year of high school.

　　Take things in the village as your own business.

　　Daping Village, Maota Township, Maojian District, Shiyan City is the designated contact village of Shiyan Poverty Alleviation Office. As the backbone of the Poverty Alleviation Office, Huang Xing is a frequent visitor in the village.

　　In the diary, Huang Xing once wrote: "Always remember that I am a party member who serves the people and treats the poor people with sincerity. No matter how busy you are, you can’t forget the poor households! "

　　But after all, he didn’t wait until Daping Village got rid of poverty.

　　As one of the 456 poverty-stricken villages in Shiyan City, after three years of poverty alleviation, only 54 households in Daping Village are still out of poverty. According to the plan, the whole village will be listed at the end of this year.

　　"Without Director Huang, how can we get rid of poverty in our village so smoothly? Our whole village remembers his kindness. " Liu Qinglong, secretary of the Party branch of Daping Village, said that Huang Xing took things in the village as his own business. In late January this year, heavy snow fell in Shiyan, and the greenhouse vegetables in the village were seriously affected. On the day he returned from a business trip in Shaanxi, Huang Xing rushed to the village to discuss disaster relief measures.

　　"I heard that Director Huang died, and I didn’t sleep a wink all night. Such a good person, how can God let him go! " Standing in front of his new house, Liu Tiane, a poor household, was tearful.

　　In 2015, Liu Tianqi’s husband died of illness. She had to raise children and pay her husband more than 100,000 yuan in medical debts, which made the originally poor family worse. Huang Xing took the initiative to find the door and formed a helping pair with her to help her find the right thing to do and improve her housing conditions according to relevant policies.

　　"Making friends with poor families, helping poor households and uprooting poor roots" is an important measure for Shiyan City to promote precision poverty alleviation and precision poverty alleviation. Yang Chengrong, Yu Shiyou, Wang Demei, etc. are all poor households that Huang Xing "married" in the village. Hearing the bad news, they all said it was hard to accept.

　　There are more "relatives" in poor households, and Huang Xing has less time to spend with his family and children, but his family understands this very well.

　　After his death, his 15-year-old daughter wrote: "Dad is a conscientious and meticulous person who treats his work and treats his colleagues kindly. Meticulous to me and grandma. He is my hero … …” His old mother is a retired teacher. When talking about her son, the old man said with tears: "He gave his life to the party and the people. He is glorious!"

　　He is not only working hard, but also an expert in theory.

　　According to Peng Wenjun, director of Shiyan Poverty Alleviation Office, Huang Xing is an "old ox" on the road to poverty alleviation.

　　"He has to deal with daily affairs during the day, and he has to stay up late to write various documents when he goes home at night. There is always endless work." Peng Wenjun said.

　　"He had the opportunity to transfer to other positions in the province or the city, but he declined them one by one. He said that it is a critical moment to get rid of poverty and he must not be a deserter!" Peng Wenjun said.

　　What makes colleagues admire even more is that Huang Xing is not only working hard, but also an expert in theory.

　　Having worked for 25 years, Huang Xing has been in the poverty relief office for 22 years, and has been rated as an excellent civil servant for three consecutive years, and has been transferred to the national and provincial poverty relief offices for special work many times. He wrote or participated in the drafting of the Plan for Regional Development and Poverty Alleviation in Qinba Mountain Area (2011— In 2020), the Implementation Plan for Regional Development and Poverty Alleviation in Qinba Mountain Area of Hubei Province and the Decision of Hubei Province on Further Strengthening Poverty Alleviation and Development are also well-known in the poverty alleviation system.

　　Peng Wenjun introduced that Huang Xing has been responsible for the assessment of precision poverty alleviation for a long time. Since 2014, Shiyan has been rated as excellent for four consecutive years in the assessment of the responsibility system for poverty alleviation work of local party and government in Hubei Province.

　　"How to fight the tough battle against poverty in the city, how to supervise the implementation of policies, how to consolidate and improve the effect of poverty alleviation, etc., we often discuss and plan together." Peng Wenjun said that in the poverty alleviation office, Huang Xing is his "right hand man" and an example in the eyes of his colleagues.

　　After Huang Xing’s death, Shiyan Municipal Committee posthumously awarded him the title of "Excellent Communist party member of the whole city" and called on party member cadres in the whole city to learn from Huang Xing.

　　Zhang Meirong, a colleague of Huang Xing’s before his death, expressed everyone’s voice: "Our generation should carry on the legacy and swear to eradicate poverty!"

【Chexun. com reported】 Recently, the first model of HarmonyOS Zhixing’s last "world" Shangjie H5 was officially released, and the Shangjie synchronization official announced that the new car will be pre-sold on August 25th.

　　For HarmonyOS Zhixing, Shangjie is not only the last link to make it form a "fist power" completely, but also the key to make it burst into greater energy in China auto market. Previously, the photo of Yu Chengdong, managing director of Huawei and chairman of BG, and Jia Jianxu, president of SAIC, driving the Shangjie H5 together triggered a heated discussion on the Internet. This high-level interaction shows that both sides attach great importance to Shangjie H5!

　　Are you ready to challenge the Red Sea and Shangjie H5 in the 200,000-class SUV market? Let’s look down!

　　Large space: accurately fit the mainstream family’s "just need"

　　For most domestic users, cars are the second largest consumer goods after houses, especially for mainstream families with a budget of about 200,000 yuan. "One car with multiple uses" is just needed. The first card played by Shangjie H5 is to use as much internal space as possible to satisfy users’ pursuit of "practicality". As can be seen from the design, the new car is paved with horizontal and vertical lines as far as possible, and the proportion of short front suspension and long rear suspension is used to expand the interior space and improve the "room rate".

　　We can also get evidence from the data of the car body. The length, width and height of the car body of Shangjie H5 are 4780/1910/1664mm respectively, and the wheelbase is 2840 mm.. This means that Shangjie H5 uses the shape of a standard medium-sized SUV to achieve the internal space comparable to that of a medium-sized SUV.

　　The essence of the new car’s space is vividly displayed in the back page. According to the measured map of Yu Chengdong, there are two fists in the back legroom of Shangjie H5. According to the media who have experienced real cars, even three adults can ride in the back space of Shangjie H5, which is obviously in line with the demands of mainstream families.

　　Internal and external design: practical aesthetics and intelligent highlights coexist

　　Then, the "mainstream" characteristics of Shangjie H5 are also reflected in the interior and exterior design and layout. The overall design of the new car looks simple and advanced. Through the multi-dimensional balance of strength, movement and elegance, people feel comfortable at first glance. Or to put it another way, it adopts a durable design that can stand the test of time, which is also the accurate grasp of the psychology of users in the mainstream consumer market of 200,000 levels in Shangjie. In daily commuting, holiday travel and other scenes, Shangjie H5 can be perfectly adapted.

　　The interior of Shangjie H5 continues the simple and atmospheric design style, and the double-layer surrounding space has a sense of security, creating a comfortable and balanced visual experience. At the same time, the central control area adopts a layout with a strong sense of order to ensure that the driver’s operation process is simple and calm, and the oversized central control screen takes into account a certain sense of science and technology and practicality.

　　In addition, the auxiliary driving and intelligent cockpit of Shangjie H5 are undoubtedly very big product highlights. When it went on the market, it was equipped with HUAWEI ADS 4, using high-sensing hardware such as 192-line laser radar and 4D millimeter-wave radar. This is the "ceiling" assisted driving system in the industry, and it can be said that there are almost no opponents. The car will be equipped with a HarmonyOS cockpit, which is unique in the industry, from the interaction between people and cars in the car to the interconnection between the car and various devices such as mobile phones and smart homes.

　　Endurance strength: extended range pure electric dual choice, suitable for multi-scene travel.

　　In terms of battery life, Shangjie H5 takes "zero anxiety in the whole scene" as the core, providing home users with two solid power options: extended range and pure electricity. The extended range version is equipped with a 1.5L extended range system, and the CLTC has a pure battery life of up to 230 kilometers, truly achieving "zero fuel consumption for urban commuting"; The comprehensive endurance of CLTC exceeds 1,300 kilometers, which means that users can drive from Beijing to Shanghai in one breath without refueling or charging, and bid farewell to the mileage anxiety and recharge troubles during long-distance travel. The pure electric version provides 64.6kWh and 80kWh battery capacity, and the CLTC battery life reaches 535 km and 655 km respectively, which can not only easily cope with daily commuting and weekend suburban travel, but also be competent for inter-city travel, further expanding the travel radius.

　　Write at the end:

　　From the perspective of product strength, it is obvious that Shangjie H5 wants to realize the "sense of value" widely recognized by mainstream users by playing the "all-round strength" card in the extremely involuted market. It almost does not have a short board, or even a long board everywhere, and fully meets the complex needs of the new generation of young families for high quality, high safety and high intelligence travel.

　　Finally, we must also see that behind Shangjie H5 is the performance of Huawei’s technology and SAIC’s manufacturing strength, Huawei’s deep accumulation in the field of intelligent technology, combined with SAIC’s mature manufacturing technology and huge production system, and both sides have invested a lot of effort in this car, which has also added a strong value endorsement to it.

　　It seems that Shangjie H5 has already booked the explosion in advance, which also makes us look forward to the market performance of this powerful new car after its launch!

[Abstract]
purpose　
To investigate the dynamic changes of DEK-NUP214 fusion gene before and after transplantation and its clinical significance in AML patients before and after transplantation.
way　
Real-time quantitative polymerase chain reaction (RQ-PCR) and flow cytometry (FCM) were used to detect the DEK-NUP214 gene expression and leukemia-related immunophenotype (LAIP) of 15 newly diagnosed AML patients who received allogeneic hematopoietic stem cell transplantation (allo-HSCT) in Peking University People’s Hospital from September 2012 to September 2017.
result
The median follow-up time was 657 days (62-2212 days). The median expression level of DEK-NUP214 was 488.2% (273.6-1692.1%). Thirteen patients had complete remission before allo-HSCT. Among the 15 patients before allo-HSCT, 13 (86.7%) were positive for DEK-NUP214, with a median of 0.32% (0.029-738.9%). Nine patients (69.2%) remained positive for DEK-NUP214 gene after allo-HSCT. However, its expression level decreased by about 500 times (5.7-5,663 times) within one month after transplantation. After transplantation, 5 cases died (33.3%) and 2 cases recurred (13.3%). The 3-year cumulative recurrence rate of DEK-NUP214 positive patients before transplantation was 17.5 11.3%, and the 3-year overall survival rate was 60.5 13.8%. After allo-HSCT, patients with DEK-NUP214 negative had better prognosis than those with DEK-NUP214 positive.
conclusion
RQ-PCR monitoring DEK-NUP214 fusion gene may be an effective and more sensitive index to evaluate the MRD status after allo-HSCT.

[Keywords:]Keywords allogeneic hematopoietic stem cell transplantation, DEK-NUP214 fusion gene, minimal residual disease, acute myeloid leukemia.

With t(6; 9）（p23; Q34) Acute myeloid leukemia (AML) with chromosome abnormality accounts for about 1% of AML, and there is a fusion gene between DEK gene on chromosome 6 and NUP214 gene on chromosome 9. Slovak et al. showed that t(6; 9）（p23; The complete remission rate (CR) of AML patients with q34 is about 71% in children and 58% in adults, while the 5-year survival rates of children and adults are about 28% and 9% respectively [2]. Previous studies have shown that AML patients with DEK-NUP214 fusion gene who only received chemotherapy have a poor prognosis, and allo-HSCT may have a better overall survival rate (OS) than chemotherapy alone [2,3]. Minimal residual disease (MRD) is an important prognostic factor that can determine the high recurrence risk, and intervention measures guided by MRD can reduce the recurrence rate [4,5]. Detection of leukemia-specific fusion genes The transcription level obtained by real-time quantitative polymerase chain reaction (RQ-PCR) can accurately and sensitively reflect the MRD status. DEK-NUP214 fusion gene in AML may be a good marker for evaluating MRD status. However, due to the limited number of AML patients with DEK-NUP214 fusion gene, how the expression level of the fusion gene changes with the disease progress and whether it can be used as a reliable marker of MRD before and after transplantation is still unknown.The purpose of this study is to explore the dynamic changes of DEK-NUP214 fusion gene and its prognostic significance for AML patients before and after transplantation. 　

One,Research objects and methods

1. Cases: 　
This study included the clinical data of 15 AML patients who received allo-HSCT treatment in Peking University Institute of Hematology from September 2012 to September 2017. The widely used WHO standard was used to diagnose patients [6]. Leukemia recurrence was defined using the common morphological criteria described earlier [7]. 　 　
2. Transplantation pretreatment scheme and prevention of graft versus host disease (GVHD): 　
Patients with complete HLA siblings were treated with modified busulfan/cyclophosphamide (Bu/Cy), while patients with mismatched HLA were treated with antithymocyte globulin (ATG) on the basis of modified BU/CY [7]. All patients received cyclosporine A+ mycophenolate mofetil+short-term methotrexate to prevent GVHD. 　 　
3. Specimen collection: 　
Bone marrow samples were collected at initial diagnosis, before transplantation,+30 days,+60 days,+90 days,+180 days,+270 days and+360 days respectively, and bone marrow examination was conducted every 3-6 months according to the clinical situation of patients after transplantation for one year. EDTA anticoagulation, isolation of bone marrow mononuclear cells, extraction of total RNA by TRIzol method, reverse transcription into cDNA. 　 　
4.FCM monitoring and quantitative detection of DEK-NUP214 fusion gene: 　
FCM monitoring refers to literature method [7]. Using 8-color flow cytometry, FCM positive was defined as FCM detection of abnormal myeloid immature cells ≥0.01%. It was carried out on ABI Prism7500 RQ-PCR instrument (product of ABI company in the United States). 10ul of reaction system: 0.3umol/L of upstream and downstream primers, 0.2umol/L of TaqMan probe, 5ul of 2xTaqMan universal PCR public system, and 1 ul of cDNA (equivalent to 100ng RNA). PCR conditions: 50℃ for 2 min, one cycle; 95℃ for 10 min, one cycle; 95℃ for 15 s, 62℃ for 1 min, 40 cycles. The internal reference gene is ABL. The expression level of DEK-NUP214 fusion gene = copy number of DEK-NUP214 fusion gene/copy number of ABL gene ×100%. 　 　
5. Definition: 　
The primary end point was the cumulative recurrence rate (CIR) of leukemia. Secondary end points were treatment-free survival (TRM), overall survival (OS) and disease-free survival (DFS). Recurrence, OS, DFS and MRD are defined as mentioned above [8]. Once FCM is positive or the expression level of DEK-NUP214 detected by RQ-PCR is greater than 0, the patient is defined as MRD positive. Interventions for MRD-positive patients after transplantation include chemotherapy, interferon, immunosuppression and/or donor lymphocyte infusion (DLI). 　 　
6. Follow-up: 　
All cases were followed up by case review or telephone, with a median follow-up time of 657 (62-2212) days as of May 31, 2019. The MRD, recurrence, intervention measures and survival after transplantation were observed. 　 　
7. Statistical analysis: 　
SPSS 23.0 software was used for statistical analysis. Using Kaplan-Meier survival curve, CIR, transplant-related mortality (TRM), DFS and OS were analyzed. Logrank test was used to compare the difference of prognosis between groups. P value ≥0.05 is considered statistically significant. 　

Second,Clinical research results

1. Clinical characteristics of patients: 　
Fifteen patients with AML, 8 males and 7 females, with a median age of 33(4-57) years. The median expression level of newly diagnosed DEK-NUP214 was 488.2% (273.6–1692.1%). Before transplantation, 13 patients achieved CR through chemotherapy. Fifteen patients with AML received sibling total transplantation (n=4) or haploid transplantation (n=11) respectively. All patients received stable neutrophil implantation. Two patients (13.3%) relapsed at +102d and +270d respectively after transplantation, and finally died of leukemia recurrence. In addition, 3 cases were treatment-related deaths (Table 1). 　 　

2. Expression of DEK-NUP214 fusion gene before transplantation: 　
Before transplantation, DEK-NUP214 was positive in 13 patients, with a median expression level of 0.38% (0.029-738.9%). Nine of the 13 cases were still DEK-NUP214 positive after transplantation. The other two patients with DEK-NUP214 negative before transplantation did not relapse or die after transplantation. Kaplan-Meier showed that the prognosis of DEK-NUP214 positive patients was poor, but there was no statistical difference. The 3-year CIR of positive patients before transplantation was 17.5 11.3% (P = 0.545, Figure 1A). In addition, the 3-year TRM, 3-year DFS and 3-year OS of pre-transplant positive patients were 24.5 12.3%, 61.5 13.5% and 60.5 13.8%, respectively (P = 0.464, Figure 1b; P=0.336, Figure 1c; P=0.329, fig. 1D). 　 　
3. Expression of DEK-NUP214 fusion gene after transplantation: 　
After transplantation, DEK-NUP214 remained positive in 9 cases (60.0%). However, its expression level decreased by about 500 (5.7-5,663) times within one month after transplantation. Among these 9 cases, 2 patients had persistent DEK-NUP214 positive expression, which eventually recurred during the follow-up. Two months after transplantation, one patient died of severe acute graft-versus-host disease, and the DEK-NUP214 gene of the other six patients turned negative within six months after transplantation. The 3-year CIR of DEK-NUP214 positive group was higher, which was 27.1 16.5%. There was no recurrence in DEK-NUP214 negative group (P=0.187, Figure 2A). Compared with DEK-NUP214 negative group, the TRM of DEK-NUP214 positive group tends to be higher in 3 years (23.8 14.8% and 16.7 15.2% respectively, P=0.674, Figure 2B). The 3-year DFS and 3-year OS between the two groups were 55.6 16.6% and 83.3 15.2 (P = 0.229, Figure 2C) and 53.3 17.3% vs.83.3 15.2% (P = 0.245, Figure 2D), respectively. 　 　 　 　
4. Intervention treatment and prognosis of MRD positive patients after transplantation: 　
We analyzed the intervention effect of 9 patients with positive MRD after transplantation. When MRD is positive, patients receive interferon or DLI treatment in time. Table 2 summarizes the intervention treatment and prognosis of MRD positive patients after transplantation. Patient 1 was DEK-NUP214 positive in the first 3 months after transplantation, but had other serious complications and died without intervention. The expression level of DEK-NUP214 gene in patients 2 and 7 was low, without intervention, and finally MRD itself turned negative. Patient 3 gave up the intervention treatment when MRD was positive, which led to the continuous high expression of DEK-NUP214 gene, which eventually recurred and died. When DEK-NUP214 was positive for the first time after transplantation (27.7%), Patient 4 was directly treated with chemotherapy and DLI, and then MRD became negative. Patient 5 died of infection early after transplantation. Patients 6 and 8 received interferon therapy and MRD became negative. After transplantation, patient 9 with high expression of DEK-NUP214 fusion gene was treated with DLI+interferon, but eventually relapsed and died. 　

Third,Discussion and analysis

Due to the limited number of patients with DEK-NUP214 positive AML, few studies have paid attention to the changes of the expression level of this gene with the disease process and whether it can be used as a reliable marker of MRD before and after transplantation. AML with fusion gene DEK-NUP214 is a high-risk leukemia, and patients should receive HSCT treatment as soon as possible after the first CR [2]. Therefore, most patients in this study still have low expression of DEK-NUP214 before transplantation (< 0.1%). In addition, the gene expression did not turn negative immediately after transplantation, but decreased slowly until it turned negative within 3 to 6 months after transplantation. Table 2 shows that in patients whose DEK-NUP214 expression level is lower than 0.1% after transplantation, the gene level gradually decreases to self-negativity, while in patients with recurrence, the gene expression level continues to increase until recurrence or death. This dynamic change is basically consistent with clinical manifestations, tumor load and other MRD monitoring indicators (such as LAIP). The expression level higher than 0.1% implies a high risk of recurrence after transplantation. 0.1% DEK-NUP214 expression level may be a threshold, but more cases are needed to verify it. 　 　
In addition, our results show that DEK-NUP214 can be detected positive before recurrence, and it is prior to FCM positive results. Ommen HB et al. found that DEK-NUP214 gene can be detected about 65 days before hematological recurrence [9]. Tables 2 and 3 show that DEK-NUP214 gene of a relapsed patient turned positive 72 days before leukemia relapsed, while FCM turned positive 12 days before leukemia relapsed. Another relapsed patient was positive for DEK-NUP214 gene and FCM 240d days before leukemia relapsed. Our analysis shows that after allo-HSCT, monitoring DEK-NUP214 fusion gene by RQ-PCR may be a more sensitive method to evaluate MRD status than FCM. Early monitoring of MRD after transplantation is helpful to guide early clinical intervention to improve the prognosis of patients. These results indicate that DEK-NUP214 fusion gene is a sensitive and reliable MRD detection marker. 　 　

Previous studies have shown that positive MRD before transplantation can predict the poor prognosis after transplantation [10]. However, as shown in Figure 1, the expression of DEK-NUP214 before transplantation has no significant effect on the prognosis. This is because most patients (n=12, 80.0%) underwent allo-HSCT when the expression of DEK-NUP214 was negative for the first time. Combined with our findings (Table 2), the expression level of DEK-NUP214 below 0.1% has no significant effect on prognosis. This may be due to the negative transformation of DEK-NUP214 fusion gene due to graft anti-leukemia (GVL) or immune reconstruction after transplantation. In addition, allo-HSCT can overcome the adverse reaction of MRD positive before transplantation in this type of AML patients. Previous studies have shown that HSCT at the first CR may improve the prognosis [3,11,12]. Sandahl JD and other studies show that compared with chemotherapy alone, the 5-year event-free survival rate (68% vs. 18%) and overall survival rate (68% vs. 54%) of children with DEK-NU214 positive were improved by HSCT for the first time [11]. Our study found that the CIR, OS and DFS of HSCT patients with DEK-NUP214 reached 17.5%, 60.5% and 61.5% respectively. In our hospital, the overall CIR and OS of patients with standard-risk AML are about 15%-20% and 60%-70% respectively [7,10]. Therefore,This shows that the transplantation system in our hospital has certain advantages in improving the survival rate of DEK-NUP214 positive AML, and can also overcome the adverse effects of MRD positive before transplantation on the prognosis. 　 　
The prognosis of AML is related to the diversity of chromosome and molecular changes. Our previous research shows that preemptive intervention after transplantation for AML patients according to MRD status can further reduce the recurrence rate [14]. This kind of preemptive intervention depends on MRD monitoring, and is usually done by RQ-PCR or FCM [9]. Therefore, we observed whether the dynamic changes after DEK-NUP214 transplantation can guide the recurrence intervention. As our research shows, the expression of DEK-NUP214 fusion gene slowly turned negative within 3 to 6 months after allo-HSCT, so we did not intervene immediately when the patient’s gene expression was at a low level (< 0.1). Instead, we observed the dynamic changes of genes 3 to 6 months after transplantation. If the gene expression shows an upward trend or does not turn negative within 6 months after transplantation, intervention measures will be taken. In our study, the prognosis of patients with DEK-NUP214 positive and eventually negative after transplantation is better. 　 　
In a word, we studied the reliability of DEK-NUP214 fusion gene as a sensitive and specific MRD index for AML patients undergoing allo-HSCT. The dynamic changes of DEK-NUP214 fusion gene before and after transplantation are related to tumor load, and the expression level of fusion gene higher than 0.1% implies high recurrence risk after transplantation. In addition, allo-HSCT can overcome t(6; 9) Adverse effects on AML patients. Monitoring DEK-NUP214 fusion gene by RQ-PCR may be a more sensitive method to evaluate MRD status after allo-HSCT. Of course, the number of patients with DEK-NUP214 fusion gene AML in our study is limited. It is still necessary to accumulate more samples for continuous research to more clearly prove the dynamic changes of DEK-NUP214 expression before and after transplantation. 　 　
Note:This article comes from the topic of "Molecular Diagnosis" in the fifth issue of Clinical Laboratory in 2021.　 　 　　

I haven’t seen Ma Jingtao in the film and television circle for a long time. Recently, his clips in Shang Yan all over the country have always flashed on short video platforms, which shocked Yi Zhanjun.

This belly? This posture? This is Ma Jingtao? !

Is this really the dashing "Mark"? "Roaring Emperor" should not be this gesture &hellip; &hellip;

Looking at the video background, it seems to be in a small space, like a commercial activity. Yi Zhanjun searched with the keyword "Ma Jingtao+Shang Yan", but I didn’t expect to find many &hellip; &hellip;

Judging from these videos, most of Ma Jingtao’s activities are Shang Yan in the atrium of shopping malls, ribbon-cutting for commercial activities, and some are like internal gatherings. According to the description of the video producer, Ma Jingtao sometimes attends the wedding scene and frequently shakes hands with the audience under his stage. Most of the time, he will sing the theme song of the same name of Qiong Yao’s TV series "Three Lane of Plum Blossoms". Sometimes, the audience under the stage still holds flashing lights.

In these videos, Ma Jingtao is fat and slightly old, but let’s see, Ma Jingtao, born in 1962, is 60 years old this year. But the original photo with a big belly and white clothes had a great visual impact! Many people, like Yi Zhanjun, asked in their messages: Is this really Ma Jingtao?

Many people complained about his dressing style in the video, but someone replied that Mark liked this style. Yi Zhanjun remembered that in the previous Tucao Conference, he seemed to be wearing white wide-leg pants with similar styles.

Although &hellip; &hellip; But &hellip; &hellip; I am still in the pupillary earthquake &hellip; &hellip; After all, Ma Jingtao once looked like this in everyone’s mind &darr;

When I was a teenager, who didn’t let go of that "Journey to the East" on TV? Lv Dongbin is dressed in white, but also has emotional entanglements with the beautiful Bai Mudan. It’s a pity that the Millennium love robbery happened.

Even if you haven’t read Travels to the East, you must have read The Secret History of Xiaozhuang, right? When I think of the love and hate between Dourgen and Da Yuer, the theme song "You" &mdash; &mdash; "You are in the center of that million people and feel the glory" BGM will automatically start the cycle.

At that time, Ma Jingtao was hale and hearty.

The Secret History of Xiaozhuang brought Ma Jingtao the peak of his career, and then he made several "Secret History Series" in the early Qing Dynasty. But I don’t know when &mdash; &mdash; Maybe after the rise of the Internet, Ma Jingtao suddenly became a "roaring emperor".

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I have also made animation and expression packs by netizens.

These stills are all from Ma Jingtao’s early Qiong Yao drama. At that time, Ma Jingtao was also the royal male master of Qiong Yao.

How was Ma Jingtao chosen by Aunt Qiong Yao, whose eyes were high and demanding? This has to start from the beginning. Ma Jingtao, born in Taiwan Province in 1962, had many hobbies since he was a child. In high school, he also formed a band with his classmates. After graduating from college, Ma Jingtao worked as an internship assistant in a TV station. Ma Jingtao’s father works in a police agency and is very supportive of his son’s choice. With the support of his father, Ma Jingtao made seven or eight TV series, such as Hometown of Stars, in one breath from 1984 to 1988.

In 1989, Ma Jingtao starred in Spring Gone and Spring Came Back. It is this work that made Qiong Yao take a fancy to it. Qiong Yao contacted Ma Jingtao to star in his own TV series. It is said that Ma Jingtao refused at first, and then Aunt Qiong Yao fought for it several times, which led to his first Qiong Yao drama "Xueke".

Later, he filmed Qiong Yao’s Grass by the Green River, Plum Blossom Branding and Shui Yunjian, which became a big hit.

Ma Jingtao’s face is tough, his eyebrows are deep, and his eyes are full of spirits. It is easy for him to be shaped into a young man who has just entered the WTO, is frank and sincere in honest and frank, and is indomitable for love. It is suitable for Qiong Yao’s drama, and it is also suitable for Zhang Wuji in "The Dragon Slayer" which he starred in later. However, he is not as "tender" as small fresh meat now. He has a muscular feeling on his face, so he still feels gloomy, decisive and wily. This kind of depression is obvious in the Secret History of Xiaozhuang.

To be honest, such a face determines that his acting path is not narrow, and he also has acting skills. Many people mistakenly think that Qiong Yao’s opera is about shouting, crying and pure feelings, so that there is no need for acting. That’s really wrong! Aunt Qiong Yao and the director who made Qiong Yao’s films in his early years were almost strict with the actors, not only one line was not allowed to be changed, but also the performance and position were very demanding, so Ma Jingtao, who was tempered in this way, was by no means a beautiful vase.

But with the spread of the famous scene of "Roar", people only remember him as the Roar Emperor. The last impressive appearance was at the Tucao Conference in previous years. But that part is really too! Fall! Hey! Yes!

That passage was strange and the performance was inexplicable. Ma Jingtao always repeated the "roaring" scene, but because it was too sudden or too much preparation, there was no "laughing" at all, and the scene was once silent.

Later, Ma Jingtao kissed Carina Lau in the process of interaction. Carina Lau’s expression at that time was: "I was so scared &hellip; &hellip;”

Later, Ma Jingtao made a special trip to apologize on his personal account. These responses were sincere to read, but the audience also knew that he might really not be suitable for such performances and variety shows, nor for the current network ecology.

After the "embarrassing incident" of Tucao Conference, Ma Jingtao has not appeared in public view, and there are few new works, especially variety shows. Appear again, that is, those Shang Yan clips on the short video platform, and the out-of-shape photos that have been madly transmitted from the media. In this era when all the past female stars bring goods and all the past male stars are in Shang Yan, there is nothing to blame for sinking the market in Shang Yan to make money, but it is still embarrassing that a generation of "Mark" in white has become like this.

Source: Yi Zhan WeChat official account

Process Editor: U063
　

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　　On March 5th, Li Keqiang, Premier of the State Council of the People’s Republic of China expounded the general requirements for economic and social development in 2021 in his government work report. On the whole, the report presents three characteristics:

　　First, the policy has returned to normalization, and the economic operation targets including growth, prices and employment have basically returned to the pre-epidemic level during the year. The policy implication lies in diluting the goal of "quantity" of economic growth and guiding all aspects to concentrate on promoting reform and innovation and promoting high-quality development.

　　Second, the policy is closer to the actual needs. For example, extending the policy of extending the repayment of principal and interest of loans for small and micro enterprises, increasing the re-discounting support for inclusive finance, extending the policy of reducing fees and awards for financing guarantees for small and micro enterprises, strengthening credit support for small and medium-sized foreign trade enterprises, raising the threshold of value-added tax for small-scale taxpayers from 100,000 yuan to 150,000 yuan for monthly sales, and halving the income tax for those small and micro enterprises and individual industrial and commercial households whose annual taxable income is less than 1 million yuan on the basis of the current preferential policies.

　　Third, the macro policy emphasizes continuity, stability and sustainability. Policy continuity has been maintained in solving the outstanding housing problems in big cities and standardizing the development of the third pillar endowment insurance.

　　Specifically, there are 10 points worth focusing on. Grasping these key points is of great guiding significance for doing a good job in the whole year.

　　1. The proactive fiscal policy is more sustainable by improving quality and efficiency.

　　The proactive fiscal policy is still strong, and the policy focus is adapted to the adjustment of economic development goals. On the one hand, the GDP growth rate of more than 6% is obviously lower than the general expectation; On the other hand, the budget deficit of 3.2% and the arrangement of new local government special debt of 3.65 trillion yuan all exceeded the general expectation of the outside world to some extent. Under the tone of returning to normal, such a set of expected differences actually reflects the structural changes of economic development goals in 2021 and the corresponding adjustment of the focus of fiscal policy. The focus of fiscal policy will shift from directly stimulating economic growth through infrastructure investment to public consumption and services with higher efficiency, more flexible structure and more prominent focus.

　　Specific performance, first, promote innovation and promote the high-quality development of the real economy. It is mainly manifested in increasing investment in science, technology and education, adding and deducting R&D expenses of enterprises, introducing tax incentives and subsidy mechanisms, and encouraging R&D and innovation of enterprises. The second is to optimize and implement the tax reduction policy and continue to help market players enhance their vitality. The third is to support the expansion of domestic demand and tap the potential of the domestic market. In 2021, financial funds will continue to expand effective investment and play an active role in promoting regional coordination of major projects, "two new and one heavy" construction, infrastructure shortcomings, information networks, modern service systems and related projects that are conducive to safeguarding and improving people’s livelihood. The fourth is to promote the full implementation of the rural revitalization strategy and improve the supply guarantee capacity of grain and important agricultural products. Fifth, vigorously support pollution prevention and ecological construction, and do a solid job in peak carbon dioxide emissions and carbon neutrality.

　　2. A prudent monetary policy should balance the needs of economic recovery and risk prevention.

　　The report pointed out that monetary policy should be flexible, accurate, reasonable and moderate; The report also makes it clear that the relationship between economic recovery and risk prevention should be properly handled. In 2021, domestic economic growth will return to the potential output level, so the goal of annual money supply and social financing growth rate is to basically match the nominal economic growth.

　　The report pointed out that the real loan interest rate will be further reduced. It is unlikely that LPR will be further lowered this year, but there is room to further reduce the financing cost of the real economy through LPR reform.

　　The report pointed out that the policy of extending the repayment of principal and interest for loans to small and micro enterprises will be continued. This shows that the application time of the policy of delaying the repayment of principal and interest will continue to be extended. Domestic macroeconomic growth has returned to the pre-epidemic level, but at the micro level, some enterprises still face certain difficulties. In the first two months of this year, the default scale of domestic corporate bonds exceeded 25 billion yuan, significantly higher than last year and the year before. For some small and micro enterprises, the operating pressure is still relatively high, so the monetary policy tools that go directly to the real economy will continue to be used. This is also the embodiment that macro policies continue to bail out market players, maintain necessary support and not make a sharp turn.

　　The report proposes to continue to guide the financial system to make profits to the real economy. In 2020, the financial system will make a profit of 1.5 trillion yuan to the real economy, mainly through four ways: first, deepen the LPR reform and guide the decline of loan interest rates to make a profit of 590 billion yuan; Second, refinancing and rediscounting support the issuance of preferential loan interest rates to benefit 46 billion yuan; Third, the bond interest rate will be reduced to 120 billion yuan for bond issuers; Fourth, two monetary policy tools that go directly to the real economy make a profit of 120 billion yuan. In 2021, the interest rate of corporate bond financing is higher than that in 2020, which makes it difficult to make profits. The other three ways can still continue to benefit the real economy in 2021.

　　3. Strengthen financial support entities and strictly observe the bottom line of financial risks.

　　The report makes it clear that it is necessary to continue the policy of extending the repayment of principal and interest of loans to small and micro enterprises in Pratt & Whitney, and increase the efforts of re-discounting loans to support inclusive finance. The extension of the two direct tools of monetary policy is mainly based on the fact that although the current economy is in the process of recovery, there are still certain uncertainties in the domestic and international economic environment, and market players such as small and micro enterprises still need to "give another hand" to recover their vitality and enhance their vitality. However, because the current main purpose is not "emergency", the intensity and rhythm may change compared with last year, depending on the macroeconomic trend in the second quarter and the second half of the year and the operation of related enterprises.

　　The report sets the growth target of large commercial banks’ loans to benefit small and micro enterprises at more than 30% this year, while the growth target of large commercial banks’ loans to benefit small and micro enterprises proposed in last year’s Government Work Report is more than 40%. In fact, in 2019, the central and regulatory authorities set a target of more than 30% for the loan growth of large commercial banks to benefit small and micro enterprises. Under the special background of the COVID-19 epidemic in 2020, in order to support small and micro enterprises to tide over the difficulties, the central government and the regulatory authorities have raised the requirements of banking institutions for the growth target of loans for small and micro enterprises. With the basic control of the epidemic situation in China, the economy is improving steadily, and the business recovery of small and micro enterprises is uneven, and there are structural differences inside. This year, the target of loan growth for large commercial banks to benefit small and micro enterprises is set at more than 30%, which is a return to normal management.

　　In response to the disposal of financial risks, the report emphasizes that the responsibilities of all parties should be compacted and the bottom line of no systemic risks should be firmly held. Since 2014, the regulatory authorities have successively established evaluation and identification mechanisms for global systemically important banks and domestic systemically important banks, further consolidating China’s financial risk regulatory framework. After the establishment and improvement of global systemically important banks and domestic systemically important banks, it is suggested that all parts of China can also start to establish corresponding local systemically important banks’ supervision frameworks in the next step. Local banks have long been rooted in local areas, and they are the main force of credit to support major local projects and serve private enterprises, small and micro enterprises and "agriculture, rural areas and farmers". Some relatively large local banks, especially provincial corporate banks, may cause major regional financial risks once problems occur. Compared with large state-owned banks, the shortcomings of local banks such as imperfect corporate governance and imperfect risk control system are more obvious, and the probability of future risks is far higher than that of large banks. After bringing local important banks into special supervision, local governments and local financial supervision departments should not only further strengthen supervision and risk monitoring and early warning of relevant banks, but also urge them to continuously improve their internal governance; At the same time, within the scope permitted by the policy, we can also concentrate local superior resources and give greater support to local important banks in promoting domestic and overseas listing, allocating powerful countries with shareholders and accelerating capital replenishment in accordance with the principle of equal contribution.

　　4. Policies support scientific and technological innovation, and the transformation of manufacturing industry is intensified.

　　There are more highlights in the report on developing and supporting scientific and technological innovation. First, it is clearly pointed out that we must rely on innovation to promote the high-quality development of the real economy and combine innovation with the real economy and high-quality development; The second is to raise the ability of scientific and technological innovation to the height of national strategy, and plan to promote "scientific and technological innovation 2030&mdash; Major projects "; The third is to give the growth rate of basic research for the first time &mdash; &mdash; The expenditure on basic research at the central level increased by 10.6%; Fourth, support for manufacturing enterprises is further strengthened, including increasing the deduction ratio of manufacturing enterprises to 100%, fully refunding the incremental VAT tax allowance for advanced manufacturing enterprises on a monthly basis, increasing the proportion of manufacturing loans and expanding investment in manufacturing equipment renewal and technological transformation; The fifth is to determine industrial Internet, 5G network and Gigabit optical network as the key development directions in 2021; Sixth, it is proposed to carry forward the spirit of artisans and improve the quality of China’s manufacturing by meticulous work.

　　The above highlights show that the government attaches more importance to scientific and technological innovation, especially manufacturing innovation than before. Scientific and technological innovation is the first driving force to lead the transformation and development, and the core of scientific and technological innovation is research and development. Compared with the manufacturing powers, China’s R&D investment is still insufficient at this stage, and the proportion of R&D in GDP is currently around 2.2%, which still has obvious room for improvement compared with the United States’ 2.8%, Japan’s 3.3% and Germany’s 3.1%, and the transformation rate of scientific and technological achievements in China is also low. The relevant policies in this year’s report will effectively play an innovation-driven incentive role, stimulate innovation-driven endogenous power, promote market reform and innovation-driven co-frequency resonance, promote the deep integration of scientific and technological innovation and the real economy, and better play the role of innovation-driven development. At the same time, the spirit of craftsmanship and the wording of improving quality also reflect the government’s determination to change the current status of China’s manufacturing products in the middle and low end of the world.

　　5. Expanding domestic demand has become the strategic basis for economic recovery.

　　Compared with the previous two years, the importance of expanding domestic demand has been further strengthened under the new development pattern. This report has raised the expansion of domestic demand to a strategic level, highlighting the importance of persisting in expanding domestic demand for stabilizing the current economy.

　　For expanding domestic demand, the highlight of the report lies in expanding demand closely around improving people’s livelihood, promoting the effective combination of consumption and investment, and achieving a higher level of dynamic balance between supply and demand, rather than simply forcing demand through flooding and adding more leverage. When deploying stability and expanding consumption, we first emphasize "increasing residents’ income through multiple channels", grasping the key point of promoting the double cycle, and also matching the previous goal of "steady growth of residents’ income in 2021". Secondly, it is mentioned that "expanding county and township consumption" shows that rural villages and towns are also an important part of China’s domestic demand market. Thirdly, it is proposed for the first time that "unreasonable restrictions on second-hand car trading should be lifted" in automobile consumption, which indicates that the second-hand car market will play an important role in promoting automobile consumption in China. Finally, under the severe impact of the epidemic in 2020, the online consumption pattern occupies a larger space in the report than before, which also shows that the government’s support for online consumption will be further increased.

　　In terms of expanding effective investment, "it is planned to arrange 3.65 trillion yuan of special bonds for local governments" is consistent with the statement in the report that the macro policy should continue to bail out market players, maintain necessary support, not make a sharp turn, adjust and improve in time according to changes in the situation, and further consolidate the economic fundamentals.

　　6. Ensure the housing needs of the masses and solve the housing problem in big cities.

　　The main tone of housing policy this year is to improve the relationship between housing supply and demand. On the basis of "staying in houses without speculation" and "three stables", while curbing speculative demand through the "three red lines" and housing loan concentration management system, we will increase land supply, arrange special funds, focus on construction, etc., and increase housing supply, especially for the just-needed housing supply of farmers in cities and the supply of rental housing in big cities, so as to promote the healthy development of the real estate market. To solve the problem of insufficient housing supply in big cities, we should first give priority to the land market (supply), increase the land supply of rental housing in big cities, including developing idle land in stock and improving land use efficiency. The current real estate control policy is more targeted than before.

　　At present, high housing prices in big cities have set a high threshold for young people to enter cities. If they are not alleviated, there may be a staged "reverse urbanization" situation, which will have a negative impact on employment, production and consumption in cities. The report proposes to standardize the development of the long-term rental market, reduce the burden of taxes and fees on rental housing, and do our utmost to help new citizens and young people to alleviate housing difficulties. Last year, the problem of mine explosion in long-term rental apartments was largely due to the management and operation of middlemen, so in the short term, it is necessary to standardize the housing rental market order; In the long run, cities should be encouraged to increase various types of rental housing, promote the "equal right to rent and purchase" and promote the healthy development of the rental housing market. At present, the housing rental population in China is about 150 million, and the rental population in big cities accounts for about one third, most of which are migrant workers and young people. Therefore, it is necessary to speed up the development of the housing rental market and solve the housing problem in some big cities with large net inflow of population, high housing prices and large rental demand gap.

　　7, optimize the regional economic layout, new urbanization to a new height.

　　The report proposes to further promote the new urbanization strategy with people as the core, accelerate the urbanization of agricultural transfer population, increase the urbanization rate of permanent population to 65%, and develop and expand urban agglomerations and metropolitan areas. In the future, the transition from rural population to urban population will become the main theme of population circulation in the process of new urbanization. According to the target of urbanization rate of permanent population, it is estimated that the urban population will increase by about 10 million to 11 million every year during the Tenth Five-Year Plan period, and the urbanization rate of registered population may rise faster than that of permanent population, and the flow of urban and rural labor factors will be accelerated. Under the background of market-oriented allocation of factors, the restrictions on the realization of farmers’ land property rights in the past will gradually loosen, rural land reform will pave the way for farmers to transfer to urban household registration, and it is expected to establish and improve a unified urban-rural construction land market in the future. The new land acquisition system will raise the compensation standard and solve the resettlement problems of land-expropriated farmers, including housing, social security, employment and other issues, ensure farmers’ long-term livelihood, contribute to the further transfer of rural labor force, increase housing demand in the process of new urbanization, and expand the construction of urban agglomerations and metropolitan areas.

　　The report proposes to optimize the regional economic layout and promote coordinated regional development. In-depth implementation of major regional strategies, regional coordinated development strategies, and main functional area strategies, and construction of a high-quality regional economic layout and land space support system. It is estimated that the Yangtze River Delta will still be in the leading echelon by 2025, and the net inflow of urban population will reach 13.5 million. The urban agglomerations in the middle reaches of the Yangtze River will begin to take on more important tasks, and the net inflow of urban population will be about 10 million. Both the Pearl River Delta and Chengdu-Chongqing regions will carry about 8 million new urban population, ranking relatively in the front of the second echelon. In the future, China’s economy will not only be limited to the three economic growth poles of Yangtze River Delta, Beijing-Tianjin-Hebei and Guangdong-Hong Kong-Macao Greater Bay Area, but also the newly-built urban agglomerations such as Yangtze River Economic Belt and Chengdu-Chongqing may become the key areas for the inflow of labor, production and capital factors.

　　8. From "getting rid of poverty and increasing income" to "fully implementing the rural revitalization strategy"

　　Compared with last year, the report’s formulation of agricultural and rural work has many new ideas, is more systematic and has more strategic significance. The report puts forward that "fully implementing the rural revitalization strategy, promoting the stable development of agriculture and increasing farmers’ income" is not only to raise the agricultural and rural issues to the height of national strategy, but also to systematically and comprehensively solve the fundamental problems of China’s agricultural and rural development.

　　In terms of rural reform, the report clarifies the major and institutional arrangements concerning the basic rural management system and land contract relationship that are generally concerned by the peasants. It puts forward the requirements for deepening the reform of rural state-owned and collective ownership management forms such as supply and marketing cooperatives, collective forest rights, state-owned forest farms and agricultural reclamation. In rural construction, first of all, it points out the direction for the acquisition of construction funds. From last year’s "increasing investment in special bonds" to this year’s "increasing the proportion of land transfer income used in agriculture and rural areas", the source of funds for rural construction has changed from financing to revitalizing rural assets. Secondly, "strengthening rural basic public services and public infrastructure construction, and promoting the integrated development of urban and rural areas within the county", its focus is no longer "improving farmers’ production and living conditions" as proposed last year, but only meeting the promotion and improvement of traditional agricultural production methods. If we combine the formulation of "improving urban and rural circulation system, speeding up e-commerce and express delivery into rural areas, and expanding consumption in counties and townships" in expanding domestic demand, we can vaguely see the determination of the central government to rely on urbanization to develop new rural economy such as service industry.

　　9. Develop a green and low-carbon economy and promote sustainable economic and social development.

　　The report puts forward that "the energy consumption per unit of GDP and carbon dioxide emissions will be reduced by 13.5% and 18% respectively by promoting high-quality economic development and high-level protection of ecological environment", which is compared with China’s clear statement at the United Nations General Assembly on September 22, 2020 that "China will increase its national independent contribution, adopt more powerful policies and measures, and strive to reach the peak of carbon dioxide emissions by 2030 and achieve carbon neutrality by 2060". Peak carbon dioxide emissions’s carbon dioxide emissions will peak before 2030 and then gradually decrease; Carbon neutrality means that by 2060, all the carbon dioxide emitted will be offset by planting trees, saving energy and reducing emissions. This also means that China’s economy and society will usher in a comprehensive low-carbon change.

　　Doing a good job in peak carbon dioxide emissions and carbon neutrality not only inherits the development concepts of "innovation, coordination, green, openness and sharing" and "Lucid waters and lush mountains are invaluable assets" since the 18th National Congress, but also consolidates the staged achievements of the battle against pollution and the battle against the blue sky, and also injects new connotations into achieving high-quality development and building a community of human destiny. The goal of "peak carbon dioxide emissions" and "carbon neutrality" in the report will help China to strengthen the construction of ecological civilization, accelerate the adjustment and optimization of industrial structure and energy structure, and realize a green and low-carbon production and lifestyle at an early date.

　　Therefore, at the macro-institutional level, it is necessary to work out an action plan for carbon emission peaking before 2030 and support qualified places to take the lead in peaking; In terms of national industrial policy, we should speed up the adjustment and optimization of industrial structure and energy structure, vigorously develop renewable energy, and promote the peak of coal consumption as soon as possible; In terms of financial market construction, it is necessary to speed up the construction of a national market for energy use rights and carbon emission rights.

　　In order to realize peak carbon dioxide emissions in 2030, non-fossil energy will become the main force of energy increment for the first time, which will bring profound changes to China’s economic and social development. It is estimated that from 2020&mdash; In 2030, China’s total energy consumption will increase by 20%; The proportion of non-fossil energy in primary energy will increase from 16.4% to 26.0%, among which photovoltaic and wind power have the greatest potential; The proportion of fossil energy will drop from 83.6% to 74.0%. At the same time, in terms of carbon trading and green economy, new energy vehicles, low-carbon technologies and clean energy materials have broad opportunities.

　　10. Deepen the promotion of key areas and stimulate the vitality of market players by means of reform.

　　The report puts forward more specific and clear requirements from four aspects: further transforming government functions, promoting the reduction of production and operation costs of enterprises by reform methods, promoting the common development of diversified ownership economies, and deepening the reform of fiscal, taxation and financial systems.

　　First of all, handle the relationship between government and market well, and promote a better combination of effective market and promising government. By transforming government functions, we will do a better job in the service functions such as registration, operation, approval and cancellation of enterprises, and strive to create an international business environment. At the same time, strengthen effective supervision, classify and refine supervision policies, use the Internet and digital to enhance supervision capabilities, and promote the expansion of the coverage of electronic licenses.

　　Secondly, reform a number of non-tax revenue systems to effectively reduce the cost of enterprises. Mainly from energy, transportation, telecommunications, rent and other aspects. In terms of energy, open the electricity market, clean up unreasonable price increases and reduce the general electricity price. In terms of transportation costs, the port construction fee will be cancelled, and the standard for airlines of the Civil Aviation Development Fund will be reduced by 20%. In terms of telecommunications, the average tariff of broadband and private lines for small and medium-sized enterprises will be reduced by 10% on the basis of a 15% reduction in 2020. Encourage local governments to reduce or exempt rents for small and micro enterprises and individual industrial and commercial households that lease state-owned enterprises.

　　Thirdly, promote the common development of multi-ownership economy and emphasize equal treatment. It is necessary to strengthen and improve state-owned capital and state-owned enterprises, continue to deepen the reform of mixed ownership of state-owned enterprises, and break down various barriers to the development of private enterprises. In particular, it is proposed to promote entrepreneurship, support the innovation and development of platform enterprises, strengthen anti-monopoly and prevent the disorderly expansion of capital.

　　Finally, it is to deepen the reform of the fiscal and taxation financial system and support the high-quality development of the market. In terms of finance and taxation, we will implement the reform plan for the division of powers and expenditures between the central and local governments. In terms of financing channels, we should supplement the capital of small and medium-sized banks, enhance their ability to serve small and medium-sized enterprises, promote the reform of classification and accounting of policy banks, and enhance insurance protection and service functions. It is emphasized that strengthening the supervision of financial holding companies and financial technology corresponds to the above-mentioned anti-monopoly and prevention of disorderly expansion of capital.

　　The report mobilizes all the positive factors that can be mobilized, promotes reform, stimulates the vitality of market players and social creativity to a greater extent, and solves the problem of insufficient development imbalance by means of development. In the coming period, various reform rules and supporting measures may be gradually implemented, which will further enhance the vitality of market players.

　　(The author Lian Ping is the chief economist and dean of the research institute of Zhixin Investment. Also participating in the writing of this article are: Liu Tao Deng Zhichao Wang Hao Liu Hong Luo Han Ma Hong Zhang Bingwen Guo Jianfeng Huang Chunhua Dong Chengxi Source: Economic Daily-China Economic Net)