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Gilead scientific Inc.

The symptoms of the first confirmed patient in novel coronavirus in the United States improved rapidly after using a new antiviral drug, Remdesivir. On January 31st, local time, Merdad Parsey, the chief medical officer of Gilead, the developer of this new drug, issued a statement in official website, saying that Remdesivir has not been officially listed anywhere in the world, but it is conducting trials in cooperation with the health department of China.

The statement mentioned that Gilead is working closely with the global health department to carry out appropriate experiments on the anti-epidemic effect of Remdesivir. These cooperative departments include the World Health Organization (WHO), China CDC and National Medical Products Administration, the US CDC, the US Food and Drug Administration and the US Department of Health.

The statement stressed that Remdesivir has not been approved for listing anywhere in the world, and its safety and effectiveness have not been confirmed. At the request of the attending doctor and with the support of the local regulatory authorities, after weighing the advantages and disadvantages of using experimental new drugs, Gilead provided Remdesivir to a small number of patients in novel coronavirus for emergency treatment when there was no other choice.

In addition, Gilead is cooperating with the health department of China to establish a randomized controlled trial to determine whether Remdesivir can be safely and effectively used against novel coronavirus, and Gilead will also speed up the appropriate laboratory tests.

According to the statement, although there is no antiviral data of Remdesivir against novel coronavirus at present, its performance against other coronaviruses gives people hope. Remdesivir has proved the activity of MERS and SARS virus in vitro and in vivo in animal models, and has also accumulated limited clinical data in the emergency treatment of Ebola infected patients.

Headquartered in Foster, California, USA, Gilead is a research biopharmaceutical company. Remdesivir is a new drug developed by the company to fight Ebola virus, which can inhibit RNA-dependent RNA synthetase.

According to the latest diagnosis and treatment process of the first confirmed case in the United States published in the New England Journal of Medicine, the patient received intravenous infusion of Remdesivir on the seventh day of hospitalization, and no oxygen was needed the next day, leaving only dry cough and runny nose.

It is worth noting that on January 28th, Wuhan Institute of Virology, Chinese Academy of Sciences and Institute of Toxicology and Drugs, Academy of Military Medical Sciences also mentioned Remdesivir. The above-mentioned institutions jointly discovered three existing drugs, namely Remdesivir (GS-5734), chloroquine (Sigma-C6628) and Ritonavir, which have good inhibitory effects on novel coronavirus (2019-nCoV) at the cellular level. Its subsequent clinical use is going through relevant procedures for approval.

Original title: Keep You Safe: Warm heroism in intertextual narration

As a unique cultural phenomenon in human society, rumors map the power structure in a specific period and intervene in the operation of real society with virtual emotional shocks. The sinologist Kong Lifei’s "Calling the Soul" tells the operating mechanism of traditional social rumors; The director dissects the rumor production mode in the network age through intertextual narration that spans the cyberspace and the real society, and praises the warmth of ordinary people with heroic romantic narration.

Rumors of Intertextuality: Ethical Dilemma in Dual Narration

Wei Ping-an, the hero of the movie "Keep You Safe", lives by selling cemeteries and is down and out. His client, Han Lu, was slandered after his death. Wei Ping ‘an sees rough roads, but he also falls into new rumors. At the beginning of "Keep You Safe", the core conflict of the whole film was directly presented to the audience. Rumors that are constantly fermenting in cyberspace eventually overflow the virtual world, changing the real fate of the dead, and also holding Wei Pingan, a cemetery agent, pushing his career to the edge of a dangerous cliff.

The victims of online "yellow rumors" are the dead who can’t prove their innocence, and there are no relatives who defend the dead. They have also taken a stand by while connecting orphanages with millions of donations. Although the rumors that are hard to match will soon be "sealed by the coffin" due to the lack of discourse confrontation, and will soon be forgotten, the Internet memory mechanism of "flying geese and leaving a sound" can completely change the life image of rumor victims. It is precisely this that stimulated Wei Pingan, who could have stayed out of it. He jumped into the whirlpool of "yellow ballads" at the risk of his life, trying hard to distinguish right from wrong and to compete with the huge and secret network power.

Once involved in this grand "yellow rumor" carnival, Wei Ping-an is like a lantern bearer in the "dark forest law", replacing the late Han Lu as a new prey of online rumors — — Not only is his relationship with Han Lu distorted, but even his just "criminal record" that he was jailed for standing up for his friends will become a new rumor that cannot be said.

The intertextuality between Wei Ping-an and Wei Ping-an is the reality rumor impact that Wei Ping-an’s daughter Wei Mo faced. If Wei Mo-li, who witnessed the truth, wants to expose rumors, he will be reviled by rumor makers like Wei Ping-an and become a new "back-pot man" and "scapegoat".

The similar experience of Wei’s father and daughter directly points to the ethical dilemma in the operation of rumors. In the anonymous field of the internet, rumors are only the entrance to the carnival of words and imagination, and also the outlet for netizens to vent their pressure. The existence of rumors satisfies the spiritual pleasure of rumor producers, disseminators and onlookers. Once someone wants to deprive this pleasure, he will sacrifice himself to become a new "plaything". Internet rumors use this kind of "person-to-person" pyramid scheme to ensure their vitality and value, and also deter the intervention of rumors. In real life, rumors, through the words and physical threats of rumor makers, shield the opponents of rumors from the rumor field and are ready to swallow up the rumors at any time. Whether in virtual space or in real life, rumors are burdened with heavy mental pressure and suffer in the ideological struggle of watching and intervening.

As the film says: "When you open your mouth and say that a woman is a lady, whether she is or not, she is already." The production of rumors does not require cost, but to compete with rumors, it requires the rumors to constantly consume themselves until they fall into an ethical dilemma of self-doubt. Compared with the film directed in 2012, the breakthrough of "Keep You Safe" is to shift the focus from the victim of rumors to the rumor-maker, and to show the chain destructive power of rumors more integrally with the structure of intertextual narration, so that the audience has a deeper understanding and vigilance against rumors in the Internet age.

Romantic warmth: heroism in daily fireworks

Wei Ping-an is an elderly citizen with no special skills, who lives by selling graves in the cemetery with the help of his former friends. But it is such a humble little person who has shouldered the banner of fighting against the "yellow rumors" on the Internet without hesitation. After losing the battle for the right to speak in cyberspace, Wei Ping-an struggled with General Feng and Chairman Wolongshan, who were eager to move their graves, to gain time. On the other hand, he "hacked" Chairman Jin, the key person in the rumor spreading chain, and finally tracked down the clues of the rumor maker. Then, it was a thrilling adventure of "riding a thousand miles". After spending a lot of time, money and energy, Wei Ping-an ended the rumor with "one-man fighting".

Walking in the same direction as Wei Ping’s rumor-dispelling trip is the spiritual growth process of Wei Li, a female middle school student, from hesitation to firmness. She was bullied on campus because of rumors. Instead of falling into depression as her parents feared, she quickly revived with blood based on the belief of "doing what you think is right", which provided a firm value support for Wei Pingan, who is thousands of miles away.

In the process of breaking the two rumors, we did not focus on social organizations and schools as representatives of power discourse, but shaped little people like Wei’s father and daughter into civilian heroes against rumors. In this rumor war, as heroes, they have no weapons to rely on, only the warmth of caring for kindness in their hearts. The film’s display of Wei Ping ‘an and Wei’s inner tenacity is actually to pin the hope of dispelling rumors and stopping rumors on the audience and every ordinary person in real life.

The production and dissemination of rumors are based on people. To eradicate rumors, we must eradicate the psychological mechanism of producing rumors and spreading rumors. In the process of Han Lu’s "yellow ballads", "Mr. Perfect 421" certainly played a fundamental role, but the pursuit of self-exposure by a large number of netizens eventually turned this insignificant snowflake, which was originally submerged in the information ocean, into a snowball that crushed the real world. In the comparative narrative of spreading rumors and dispelling rumors, the film actually raises a sharp question: which producer or disseminator played a greater role in making rumors "rumors"?

At the end of the story, the late Han Lu arranged fireworks for Wei Ping ‘an in the form of a will. Naturally, this splendid fireworks is not a thank you to Wei Pingan for defending his reputation, but a thank you for the warmth he has always kept in his heart. In the fireworks all over the sky, Han Lu’s warmth to the world and Wei Ping’s warmth to Han Lu met across time and space. The heroic portrayal of Wei’s father and daughter in the film also declares a distinct value position: "Rumors stop at the wise" does not require everyone to be observant, as long as the warmth in their hearts is not lost in the information carnival, everyone can become a hero in the fireworks world.

In the "information cocoon" of the Internet and big data, the production and dissemination of rumors are easier and faster than at any time in history, and the difficulty of dispelling rumors has reached the peak of history. Everyone can be a gossip, and naturally they can also be rumors. "Keep you safe" uses a warm heroic narrative to praise the Wei father and daughter who "don’t believe in rumors and don’t preach them"; With the warmth of heroism, I look forward to everyone who is not afraid of "tempering". (Author: Associate Professor Du Xiaojie, School of Journalism and Communication, Nanning Normal University)

　　[Editor’s note]

　　Another year of college entrance examination. The annual national unified college entrance examination is coming.

　　There are still two days before the 2023 college entrance examination. How to kick the final "one foot at the door"? Shanghai’s famous teachers have given many clever tricks to the candidates through The Paper.

　　You and I are both dark horses. May the candidates be full of passion and fighting spirit, live up to their youth and sail by dreams.

　　When candidates are nervous about preparing for the exam, their parents may be more nervous than candidates, hoping to be perfect in diet. How to prepare a reasonable diet for children and how to avoid dietary misunderstandings has become a difficult problem for many parents.

　　Ji Yuping, an advanced individual in health work in Shanghai and a health care teacher in Shanghai Gaojing No.1 Middle School, said that during the sprint of college entrance examination review, candidates need to consume a lot of energy in preparing for the exam, which is naturally inseparable from reasonable nutrition and diet every day. Good physical condition is the basis for candidates to get good grades, and a reasonable nutritious diet can effectively help candidates maintain a good learning state.

　　Ji Yuping reminded parents that nutrition, like knowledge, depends on the usual accumulation. It is not that the more good things you eat, the better. The principle of arranging meals should be nutrition, comprehensiveness, moderation and balance. As long as the diet is healthy and balanced, the food you usually eat already contains various nutrients needed by the human body, so it is not recommended to supplement health care products.

　　Five "Taboos" of Diet before Exam

　　There are still two days to go before the college entrance examination. Ji Yuping summed up five "taboos" of the college entrance examination, especially the diet before the exam.

　　1. Avoid big changes in recipes before exams.

　　Before the exam, don’t deliberately increase your diet too much, and don’t make too much changes during the exam. You should be consistent with usual. In addition, eat foods that you usually eat less carefully to avoid food allergies and intolerance. Don’t eat low-sugar and diuretic fruits before the exam.

　　2. diet is the most taboo to reduce staple food

　　Candidates’ diet should first ensure the intake of staple food, which is rich in carbohydrates. 50%-65% of the energy needed by the human body should be provided by carbohydrates in food. People who don’t eat staple food will not only feel hungry, but also affect the thinking ability of the brain.

　　3. Food should be cold and unsanitary.

　　Don’t buy things to eat in street stalls, and don’t eat or eat less cold drinks. In hot weather, parents can prepare mung bean soup, boiled water or fresh fruit at home for their children to quench their thirst. Do not eat or eat less raw and cold food such as sashimi or cold salad before the exam, and pay attention to food hygiene before eating, so as not to cause gastrointestinal diseases.

　　4. Don’t talk too much about exam topics when eating.

　　When the examinee has a meal, parents can take the initiative to talk about some pleasant topics and create a relaxed dining atmosphere, which is helpful for the secretion of digestive juice and the digestion of food.

　　5. avoid dinner before the exam

　　Recently, the number of infected people in COVID-19 has increased, so we don’t have dinner or eat in crowded places to avoid re-infection and affect the performance of the exam. Eating too much is not easy to digest, and it is mainly light before the college entrance examination.

　　So how to eat better for candidates, Ji Yuping also gave a more suitable "college entrance examination recipe".

　　Two days before the college entrance examination, especially three days before the college entrance examination, three meals a day are arranged in this way, which is nutritious and educational: a normal diet is the best tonic, and it is necessary to match the staple food with coarse and fine grain; Non-staple food, mixed with meat and vegetables. And "eat well early, eat well at noon and eat skillfully at night" is a simple but practical key to eating.

　　Eating well at breakfast helps to refresh the mind.

　　Breakfast is the basis of diet to ensure energy throughout the morning. A good breakfast should include: sweet potatoes, milk or dairy products, animal food, fresh vegetables or fruits.

　　Porridge, noodles, jiaozi and other staple foods are rich in carbohydrates, which can provide energy for the brain to use quickly, so that candidates can have a full spirit in the morning. Fried dough sticks, hemp balls, pancakes, etc. are not easy to digest because they contain a lot of fat. It is recommended to eat as little as possible for breakfast.

　　In addition, you should eat a proper amount of high-quality protein foods, such as lean slices, eggs, milk, etc. Those who are intolerant of milk and dairy products can be replaced by high-quality vegetable protein soybean products such as soybean milk and tofu brain. High-quality protein foods can not only supplement essential amino acids, increase satiety, but also prevent hypoglycemia before lunch.

　　Eating enough at lunch helps to improve intelligence.

　　Lunch is the most important meal in a day. Whether candidates can get nutritional supplements for their intense study and exams in the morning and get nutritional preparations for their hard work in the afternoon depends on lunch. On the basis of meeting children’s tastes, lunch should ensure sufficient calories and various nutrients.

　　First of all, the staple food should be sufficient to ensure the continuous supply of energy and maintain the balance between energy consumption and supply in brain tissue.

　　Secondly, high-quality proteins should be supplemented. Foods can be selected such as fish, shrimp, eggs, milk, chicken and lean meat, especially deep-sea fish, which are rich in EPA and DHA. Lecithin in EPA, DHA and egg yolk can protect eyesight, improve cerebral cortex function and enhance memory.

　　Third, we should pay attention to supplementing other nutrients, such as B vitamins, vitamin C and minerals such as calcium and zinc, among which vitamin C can promote the absorption of iron in food and increase the utilization of oxygen in brain tissue; Adequate calcium can inhibit the abnormal excitement of cranial nerve and peripheral nervous system activities, calm and prevent mania.

　　Among them, fruits rich in vitamin C such as strawberries, cherries, kiwis, apples, oranges, etc. and fresh vegetables such as tomatoes, cauliflower, bitter gourd, green leafy vegetables, etc. Foods rich in calcium include shrimp, black sesame, black fungus, milk, shepherd’s purse, amaranth, rape and so on.

　　Eating at dinner helps soothe the nerves.

　　For dinner, you should make some foods that are easy to digest and moderate in calories. The staple food should not be overeated. The dishes can be bean products, lean meat, fish, fungi and vegetables.

　　When children feel tired, they can add some peanuts, cashews and walnuts, which are rich in B vitamins, vitamin E and protein, and help to restore energy. After a whole day’s review and examination, your eyes are easy to get tired. You should eat some carrots, animal livers, dark green or red, yellow and orange vegetables, etc. These foods are rich in vitamin A, which is conducive to maintaining normal vision.

Passive safety SF90 2020 3.9T V8 Stradale Main/passenger seat airbag Main ●/Deputy ● Front/rear side airbag Front ●/Back- Front/rear head airbag (air curtain) Front ●/Back- Passenger seat cushion airbag – Front middle airbag – Rear seat belt airbag – Rear seat anti-sliding airbag – Rear center airbag – Passive pedestrian protection – Runflat tire – Active safety SF90 2020 3.9T V8 Stradale ABS anti-lock braking ● Braking force distribution (EBD/CBC, etc.) ● Brake assist (EBA/BAS/BA, etc.) ● Traction control (ASR/TCS/TRC, etc.) ● Body stability control (ESC/ESP/DSC, etc.) ● ISOFIX child seat interface – lane departure warning system zero Active braking/active safety system zero Fatigue driving tips – DOW opening warning – Forward collision warning zero Rear collision warning – Sentinel mode/clairvoyance – Low speed driving warning – Built-in driving recorder – Road rescue call – Driving control SF90 2020 3.9T V8 Stradale Engine start-stop technology ● Energy recovery system – Automatic parking ● hill start assist control ● Steep slope descent – Air suspension – Electromagnetic induction suspension – Variable steering ratio – Integral active steering system – Four-wheel drive/cross country SF90 2020 3.9T V8 Stradale Central differential locking function – Wading induction system – Low speed four-wheel drive – Creep mode – Tank turn – Driving hardware SF90 2020 3.9T V8 Stradale Front/rear parking radar Front ●/rear ● Transparent chassis /540-degree image – Driving function SF90 2020 3.9T V8 Stradale Reversing vehicle side early warning system – satellite navigation system ● Navigation road information display ● AR real-life navigation – High precision map – Parallel auxiliary zero lane keeping assist system – Lane centering – Road traffic sign recognition zero night vision system – Auxiliary parking position – Remote parking – Track backwards – Auxiliary lane change – Remote summoning – Appearance/theft prevention SF90 2020 3.9T V8 Stradale Electric spoiler – Automatic door opening and closing – Frameless design door – Magic induction door – Electric trunk – Induction trunk – Electric trunk position memory – The tailgate glass opens independently. – Garage door remote control device – roof luggage rack – Engine electronic anti-theft ● Central lock in car ● keyless start system ● Hidden electric door handle – Active closed air intake grille – Battery preheating – External discharge – Vehicle wireless charging – Exterior lighting SF90 2020 3.9T V8 Stradale LED daytime running lights ● Adaptive far and near light – Automatic headlights ● Steering assist light – Steering headlight – Headlight rain fog mode – Headlight height is adjustable. ● Headlight cleaning device – Headlights are turned off with delay. ● Skylight/glass SF90 2020 3.9T V8 Stradale Sky skylight – Front/rear power windows Front ●/Back- Anti-pinch function of window – Rear windshield sunshade – Rear privacy glass – Rear wiper – Heatable water spray nozzle – Screen/system SF90 2020 3.9T V8 Stradale Rotating large screen – Central control LCD screen display – Bluetooth/car phone ● Gesture control – Face recognition – mobile TV – Rear row control multimedia – Intelligent configuration SF90 2020 3.9T V8 Stradale Internet of Vehicles – OTA upgrade – Wi-Fi hotspot – V2X communication – In-vehicle biological monitoring system – Active noise reduction – Steering wheel/interior rearview mirror SF90 2020 3.9T V8 Stradale Multifunction steering wheel ● Steering wheel shift paddle ● Steering wheel heating – Steering wheel memory ● Full LCD instrument panel ● HUD head-up digital display – Electric adjustable pedal – ETC device – In-vehicle charging SF90 2020 3.9T V8 Stradale 220V/230V power supply – Luggage compartment 12V power interface – Seat configuration SF90 2020 3.9T V8 Stradale Sports style seat – Electric adjustment of main/passenger seat Main ●/Deputy ● Adjustable button in the back row of the co-pilot seat – Electric adjustment of the second row seat – Fuzhi seat – Back table board – Second row of independent seats – Rear seat electric recline – Front/rear center armrest Front ●/Back- Rear cup holder – Audio/interior lighting SF90 2020 3.9T V8 Stradale Touch reading lamp – Air conditioner/refrigerator SF90 2020 3.9T V8 Stradale Heat pump air conditioning – Rear independent air conditioning – Rear seat air outlet – Temperature zone control ● car air purifier – In-vehicle PM2.5 filtering device – negative ion generator – Interior fragrance device – Car refrigerator –

　　recent days

　　human resources and social security department of fujian province　

　　education department of fujian　

　　Fujian Provincial Department of Finance jointly issued

　　On Doing a Good Job of College Graduates in 2023

　　Notice on the distribution of back-to-school job-seeking subsidies

　　　

　　Let’s watch it together

　　People’s Social Security Bureau, Education Bureau, Finance Bureau of each district and city, Social Affairs Bureau of Pingtan Comprehensive Experimental Zone, Finance Bureau, and colleges and universities: In order to thoroughly implement the decision-making arrangements of the CPC Central Committee and the State Council, make efforts to promote college graduates’ job hunting and accelerate the employment of graduates, with the consent of the provincial government, it is decided to issue subsidies for college graduates to return to school for job hunting. The relevant matters are hereby notified as follows:

　　First, the subsidy object

　　Unemployed college graduates from colleges and universities in the province in 2023 (excluding graduates who have provided free accommodation in their colleges and universities).

　　Second, the subsidy conditions

　　From July 1 to August 31, 2023, graduates returned to their graduate institutions across regions to participate in job-seeking recruitment activities held in the school. Cross-regional means that the residence of graduates and the location of colleges and universities are not in the same city or county, and the flow between districts in the same city is not recognized as cross-regional.

　　Third, the subsidy standard

　　Subsidies are paid to graduates with household registration in the province according to the standard of 300 yuan per person, and those with household registration outside the province according to the standard of 500 yuan per person. Each graduate can only enjoy one subsidy.

　　Fourth, the distribution method

　　(a) the funds needed for the graduates’ job-seeking subsidies are paid from the employment subsidy funds, and the pre-allocation system is adopted, and the pre-allocation is made first and then settled. (II) According to the principle of territoriality, the education authorities in each district, city and Pingtan Comprehensive Experimental Zone calculate the funds according to the number of unemployed graduates leaving schools and subsidy standards of colleges and universities within their jurisdiction, and apply for pre-allocated funds from the finance and human resources departments at the same level according to 50% of the calculated amount, and then decompose and allocate them to colleges and universities. (3) Colleges and universities shall, in accordance with the requirements of this circular, distribute subsidies to graduates who meet the conditions for distribution, and establish real-name ledgers for future reference within 3 days from the date of returning to school for job hunting. (4) Before September 20, 2023, the education authorities of all districts, cities and Pingtan Comprehensive Experimental Zone shall settle the funds with universities and human resources departments at the same level respectively according to regulations, and make up for more.

　　V. Job Requirements

　　(a) all districts and cities, Pingtan Comprehensive Experimental Zone, education, finance departments and universities should attach great importance to it, clarify the division of tasks, strengthen coordination and cooperation, and jointly do a good job in the payment of job-seeking subsidies for returning to school. (2) Local education departments should take the lead in conjunction with the people’s society and the financial department, strengthen the work guidance for colleges and universities, do a good job in supervising the use of funds, and ensure earmarking. (3) Colleges and universities should strengthen policy propaganda, ensure that qualified graduates should know everything and enjoy it, fully mobilize unemployed graduates to return to school to participate in various recruitment activities, promote early job hunting and promote early employment.

　　human resources and social security department of fujian province

　　education department of fujian

　　Fujian Provincial Department of Finance

　　July 1, 2023